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松井 三明 准教授

    修了課程: 修了年度:

取得学位・資格

MD, MSc, PhD

ResearchGate/LinkedInアカウント

mmatsui@nagasaki-u.ac.jp

経歴

I have been working in the field of maternal health. Pregnancy and childbirth are mostly physiological processes. In some cases, however, there are pathological aspects as well. Both physiology and pathology must be taken into account when considering maternal health. Unfortunately, only pathological phenomenon is focused on, as exemplified in the saying that “Every pregnancy is a risk”. Therefore, there is a huge misuse of medical interventions observed, both in developing and industrialized countries. We should strive to find an optimal point in between the two, keeping in mind that that point is variable. There is no “magic bullet” in the field of public health. We must think together how we can change this world.

教育活動

I am in charge of the two following modules

  • “Reproductive Health and Gender”Objective: to obtain necessary knowledge in order to control maternal morbidity and mortality and gender issues in developing countries.
  • “Program and Project Management”Objective: to obtain necessary knowledge and skill to manage public health program/projects in developing countries.

研究活動

  • “The impact of the improvement of the quality of care in maternity on maternal and neonatal health in health centers in Cambodia.”Outline – Evidence-based maternity and neonatal care is not well provided at health facilities in many developing countries, therefore the quality of care is substandard. However, international societies put immense pressure on the promotion of facility-based delivery regardless of the quality of care. We carry out an evaluation of maternal and neonatal conditions during labor and the postpartum period and observe the changes after an intervention, which aims to improve the quality of care during maternity.
  • “Factors of chronic malnutrition among children under 2 years old in rural Cambodia.”Outline – Approximately one out of four children aged 24 months demonstrated being “underweight” (weight for age < -2 s.d.) in rural Cambodia. This rate progressively increased with the age of the children. This study employs a prospective design to observe the changes of weight related to age and its associated factors in rural Cambodia.

現在の主な研究活動地域

Cambodia (capital – Phnom Penh, rural – Prey Veng province)

最近の5つの出版物

  1. Suto M, Takehara K, Misago C, Matsui M. Prevalence of perineal lacerations in women giving birth at midwife-led birth centers in Japan: A retrospective descriptive study. J midwife women health. in press(2015)
  2. Noguchi M, Matsui M, Osanai Y, Horikoshi Y, Takehara K, Misago C. Women-friendly childbirth experience Cambodia. J Int Health 29(4): 81.(2014)
  3. Matsui M, Sokhan U, Keth LS, Tung R.Equity gap in utilisation of emergency obstetric care service in Cambodia, from 2007 to 2009. Trop Med Int Health. 18(suppl 1): 187.(2013)
  4. Iwamoto A, Matsui M, Okabayashi H. Review of maternal, neonatal and child health integrated services in the southern four provinces in Lao PDR. Trop Med Int Health. 18(suppl 1): 186.(2013)
  5. Honda A, Randaoharison PG, Matsui M. Affordability of emergency obstetric and neonatal care at public hospitals in Madagascar. Reprod Health Matters. 19: 10-20.(2011)

メッセージ

開発途上国での妊娠,出産を安全にすること,また産む女性,生まれてくる子ども,そして家族にとってより良いものにしていくことを研究課題としています。
妊娠と出産は生理学的な事象ですが,時に合併症を伴います。よって正常から異常までの広い範囲に対応することが必要です。これらの対応とは,単に医学的なものだけではなく,次世代へ生をつなげようとする人々への、さらには社会に対しての関わりであり,そこに携わるひとりひとりの姿勢,ありようが問われるものです。
公衆衛生に関わるということは,すなわちクリアカットには割り切れない「社会的存在」としての人間の課題に取り組むことであり,この点に学問のおもしろさがあるのです。

Richard Culleton 准教授

    修了課程: 修了年度:

取得学位・資格

PhD in malaria parasite genetics

個人/所属ウェブページ

http://www.tm.nagasaki-u.ac.jp/malariaunit/Culleton_Lab/Home.html

ResearchGateアカウント

https://www.researchgate.net/profile/Richard_Culleton

LinkedInアカウント

https://www.linkedin.com/in/richardculleton/

Twitter

https://twitter.com/malariaunit?lang=en

他所属

Malaria Unit, Institute of Tropical Medicine, Nagasaki University

経歴

  • BSc (hons) Biological Sciences — University of Edinburgh, Scotland 1996-2000
  • PhD Malaria Parasite Genetics — University of Edinburgh, Scotland 2001 -2004
  • Research Assistant – University of Edinburgh – 2000 -2001
  • Research Associate – University of Edinburgh – 2004 -2005
  • International Research Fellow – Osaka University – 2005 -2008
  • Assistant Professor – Institute of Tropical Medicine, Nagasaki University – 2008 -2011
  • Associate Professor – Malaria Unit, ITM, Nagasaki University – 2011-Present

研究活動

My lab focuses on genetic and genomic approaches to identify the underlying genetic causes of medically important phenotypic differences between parasite strains. We use the rodent malaria parasites for some of these studies, but we are increasingly pursuing investigations involving the human malaria parasites in in vitro culture, and non-human primate malaria parasites such as Plasmodium cynomolgi in monkeys. We also work in malaria endemic countries on epidemiology related projects, including with P. falciparum and P. vivax in Africa, P. knowlesi and P. cynomolgi in Southeast Asia, and P. simium and P. brasilianum in South America. We are interested in ALL aspects of malariology.

現在の主な研究活動地域

  • Japan
  • Nigeria
  • Brazil

最近の5つの出版物

  1. Lu F, Culleton R, Zhang M, Ramaprasad A, von Seidlein L, Zhou H, Zhu G, Tang J, Liu Y, Wang W, Cao Y, Xu S, Gu Y, Li J, Zhang C, Gao Q, Menard D, Pain A, Yang H, Zhang Q & Cao J., Emergence of Indigenous Artemisinin Resistant Plasmodium falciparum in AfricaNew England Journal of Medicine 376 (10), 991-993 2017
  2. Abkallo H, Martinelli A, Inoue M, Ramaprasad A, Xangsayarath P, Gitaka J, Tang J, Yahata K, Zoungrana A, Mitaka H, Hunt P, Carter R, Kaneko O, Mustonen V, Illingworth CJR, Pain A & Culleton R, Rapid Identification of Genes Controlling Virulence and Immunity in Malaria ParasitesPLoS Pathogens 13(7): e1006447 2017
  3. Brasil P, Zalis MG, de Pina-Costa A, Siqueira AM, Bianco Junior C, Silva S, Areas ALL, Pelajo-Machado M, de Alvarenga DAM, Santelli ACFdS, Albuquerque HG, Cravo P, de Abreu FVS, Peterka CL, Zanini GM, Suarez-Mutis MC, Pissinatti A, Lourenco-de-Oliveira R, Brito CFAd, Ferreira-da-Cruz MdF, Culleton R, Daniel-Ribeiro CT. 2017. Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigationThe Lancet Global Health 5: e1038–46 2017
  4. Ansari HA, Templeton JT, Subudhi AK, Ramaprasad A, Tang J, Lu J, Naeem R, Oguike MC, Benavente ED, Clark TG, Sutherland CJ, Barnwell JW, Culleton R*, Cao J* and Pain A*. Genome-scale comparison of expanded gene families in Plasmodium ovale wallikeri and Plasmodium ovale curtisi with Plasmodium malariae and with other Plasmodium speciesInternational Journal for Parasitology 2016 Oct; 46 (11) :685-96 2016 2016
  5. Abkallo HM, Tangena JA, Tang J, Kobayashi N, Inoue M, Zoungrana A, Colegrave N, Culleton R, Within-host competition does not select for virulence in malaria parasites; studies with Plasmodium yoelii PLOS Pathogens 11(2): e1004628 2015

For an up to date publication list, please see:
https://scholar.google.com/citations?user=Vkx8HZwAAAAJ&hl=en

メッセージ

The Malaria Unit at the Institute of Tropical Medicine is a dynamic and cosmopolitan laboratory specializing in the genetics and epidemiology of malaria. Although we take our scientific research very seriously, we endeavour to create a fun and relaxing environment for lab members, as we believe that science should be enjoyable and rewarding for the researcher.
We work on multiple disciplines within malariology, and try to accommodate each individual lab member’s research interests. We rely on a large network of international collaborators for the vast majority of our research projects, and currently have active partnerships with researchers in numerous regions including the UK, Portugal, Saudi Arabia, Brazil, Nigeria, Kenya, Thailand and elsewhere.
All research and lab life is conducted in English (with a smattering of Swahili, Welsh and American).
Our lab offers graduate students a relaxed and informal atmosphere in which to explore their own research interests with strong academic support and guidance if required.
Potential projects available with our lab include (but are not limited to); studies of inter-species interactions between malaria parasite strains and species within mice and mosquitoes; discovery of genes involved in drug resistance/ virulence/ strain-specific immunity in rodent malaria parasites through genetic crossing and whole genome sequencing; studies involving investigation of the conditions required for optimal vectorial capacity in mosquitoes; studies on the population genetics of P. falciparum, P. malariae and P. ovale in field isolates from Nigeria.
We also strongly encourage potential graduate students to design their own research utilizing the resources of the Malaria Unit. These include the largest collection of rodent malaria parasite isolates in the world, a colony of A. stephensi mosquitoes in a state-of-the-art insectary for transmission experiments, and access to field isolates from our international collaborators.

和田 崇之 准教授

    修了課程: 修了年度:

取得学位・資格

博士(医学)

個人/所属ウェブページ

http://www.tm.nagasaki-u.ac.jp/newrect/japanese/member/wada.html

他所属

長崎大学熱帯医学研究所国際保健学分野

経歴

  • 1997/3 京都大学理学部 卒業
  • 1999/3 京都大学大学院理学研究科生物物理学科前期課程 修了
  • 2006/12 大阪市立大学大学院医学研究科 博士(医学) 取得
  • 1999/4 – 2009/3 大阪市立環境科学研究所 研究員
  • 2009/4 – 2012/12 同 主任研究員
  • 2013/1 – 2017/4 長崎大学熱帯医学研究所国際保健学分野 国際保健学分野 助教
  • 2017/5 – 同 准教授

教育活動

(これまでの経験)
・学部講義(教養)感染症と文明
生物学基礎、生態学的観点と病原体について概説
・結核分子疫学
地方衛生研究所、保健所を対象に結核対策を指向した病原体遺伝子解析について解説、実習

研究活動

分子疫学、地域公衆衛生

病原体遺伝子情報(ゲノミクス、バイオインフォマティクス)と患者情報(疫学、地理統計学)を基盤とした病原体伝播経路の追跡。結核、抗酸菌症、その他細菌感染症。

動物感染症、人獣共通感染症における病原体適応進化

獣医学、生態学領域と連携し、動物由来試料からの病原体分離、遺伝子比較から病原体の適応進化戦略を理解する。腸内細菌叢、細菌性下痢症、その他宿主認識に関わる病原体因子。
以上の2点を中心に、時系列、地理拡散、宿主適応の3つのベクトルにおける病原体(特に細菌)のふるまいを俯瞰し、基礎・応用いずれにおいても意義のある研究成果を目指す。また、これらの研究を通して培った研究技術を基に、柔軟な社会貢献を希求する。

現在の主な研究活動地域

  • 日本
  • 台湾
  • ネパール

最近の5つの出版物

  1. 和田崇之, 吉田志緒美, 柳井徳磨. 2017. ヒト,動物,環境をとりまく非結核性抗酸菌の浸淫状況と宿主適応. 日本臨床微生物学雑誌 27: 1-10.
  2. Seto, J., Wada, T., Suzuki, Y., Ikeda, T., Mizuta, K., Yamamoto, T., Ahiko, T. 2017. Mycobacterium tuberculosis transmission among elderly persons, Yamagata Prefecture, Japan, 2009–2015. Emerg Infect Dis 23: 448-455.(2017)
  3. Ban, E., Yoshida, Y., Wakushima, M., Wajima, T., Hamabata, T., Ichikawa, N., Abe, H., Horiguchi, Y., Hara-Kudo, Y., Kage-Nakadai, E., Yamamoto, T., Wada, T., Nishikawa, Y. 2015. Characterization of unstable pEntYN10 from enterotoxigenic Escherichia coli (ETEC) O169:H41. Virulence 6: 735–744.(2015)
  4. Wada, T., Iwamoto, T., Tamaru, A., Seto, J., Ahiko, T., Yamamoto, K., Hase, A., Maeda, S., Yamamoto, T. 2015. Clonality and micro-diversity of a nationwide spreading genotype of Mycobacterium tuberculosis in Japan. PLoS ONE 10: e0118495.(2015)
  5. Wada, T., Iwamoto, T., Maeda, S. 2009. Genetic diversity of the Mycobacterium tuberculosis Beijing family in East Asia revealed through refined population structure analysis. FEMS microbiology letters 291: 35-43.(2009)

メッセージ

熱帯医学は典型的な応用科学、境界医学の一つと捉えることができますが、それだけに固執すると大事なことを見落とすかもしれません。TMGHの門を叩く学生は、もとより応用面への志が高いものと思いますので、特に基礎自然科学への親和性が高く、フレキシブルな志向を持てる学生を歓迎します。

古賀 智裕 助教

    修了課程: 修了年度:

取得学位・資格

  • 医学博士(長崎大学)
  • 医師免許

個人/所属ウェブページ

http://www.med.nagasaki-u.ac.jp/intmed-1/

ResearchGateアカウント

https://www.researchgate.net/profile/Tomohiro_Koga

他所属

  • 長崎大学病院第一内科(リウマチ・膠原病内科)
  • 長崎大学病院医療教育開発センター

経歴

  • 2005年4月~2009年3月 独立行政法人国立病院機構 長崎医療センター
  • 2009年4月~2011年5月 長崎大学病院 第一内科 リウマチ・膠原病内科 医員
  • 2011年6月~2014年2月 ハーバード医科大学(Beth Israel Deaconess Medical Center, Rheumatology Division, Dr.Tsokos Lab)
  • 2014年3月~2016年11月 長崎大学病院 医療教育開発センター 助教2016年12月〜現在 長崎大学大学院医歯薬学総合研究科 分子標的医学研究センター 助教(平成28年度科学技術人材育成費補助事業「卓越研究員事業」卓越研究員)

教育活動

  • 診断学:膠原病 各論実習
  • 研修医教育
  • 指導医講習会世話人

研究活動

  • 自己免疫疾患におけるT細胞シグナル伝達に関する研究
  • 自己炎症性疾患における遺伝子解析、サイトカイン解析に関する研究

現在の主な研究活動地域

日本

最近の5つの出版物

  1. Umeda M, Koga T (corresponding author), Ichinose K, Igawa T, Sato T, Takatani A, Shimizu T, Fukui S, Nishino A, Horai Y, Hirai Y, Kawashiri SY, Iwamoto N, Aramaki T, Tamai M, Nakamura H, Yamamoto K, Abiru N, Origuchi T, Ueki Y, Kawakami A. CD4+ CD52lo T-cell expression contributes to the development of systemic lupus erythematosus. Clin Immunol. 2017 Oct 13. pii: S1521-6616(17)30567-3.
  2. Koga T, Kawashiri SY, Migita K, Sato S, Umeda M, Fukui S, Nishino A, Nonaka F, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Ueki Y, Masumoto J, Agematsu K, Yachie A, Eguchi K, Kawakami A. Comparison of serum inflammatory cytokine concentrations in familial Mediterranean fever and rheumatoid arthritis patients. Scand J Rheumatol. 2017 Sep 2:1-3. doi: 10.1080/03009742.2017.1363281.
  3. Koga T, Otomo K, Mizui M, Yoshida N, Umeda M, Ichinose K, Kawakami A, Tsokos GC. Calcium/Calmodulin-Dependent Kinase IV Facilitates the Recruitment of Interleukin-17-Producing Cells to Target Organs Through the CCR6/CCL20 Axis in Th17 Cell-Driven Inflammatory Diseases. Arthritis Rheumatol. 2016 Aug;68(8):1981-8. doi: 10.1002/art.39665.
  4. Otomo K, Koga T (co-first author), Mizui M, Yoshida N, Kriegel C, Bickerton S, Fahmy TM, Tsokos GC. Cutting Edge: Nanogel-Based Delivery of an Inhibitor of CaMK4 to CD4+ T Cells Suppresses Experimental Autoimmune Encephalomyelitis and Lupus-like Disease in Mice. J Immunol. 2015 Dec 15;195(12):5533-7. doi: 10.4049/jimmunol.1501603.
  5. Koga T, Hedrich CM, Mizui M, Yoshida N, Otomo K, Lieberman LA, Rauen T, Crispín JC, Tsokos GC. CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance. J Clin Invest. 2014 May;124(5):2234-45. doi: 10.1172/JCI73411. Epub 2014 Mar 25.

メッセージ

研究者の目を持つ臨床医としてリウマチ膠原病内科医としてクリニカルクエスチョンを基に、最終的には患者さんに還元し実用化可能な研究を行っています。希少難病とされる自己免疫疾患や自己炎症性疾患のアンメット・メディカル・ニーズを解決するため、ともに研究できる仲間を募集しています。

砂原 俊彦 助教

    修了課程: 修了年度:

取得学位・資格

博士(医学)

経歴

1994 – 2003:佐賀大学
2004 – 現在: 長崎大学

教育活動

TMGH 修士課程、熱帯医学研修課程

研究活動

デング熱媒介蚊の生態と防除等

現在の主な研究活動地域

  • 日本

最近の5つの出版物

  1. Sunahara T. 2019. Effects of filling catch basins with Mosquito Eliminating Mat on mosquito populations. Medical Entomology and Zoology (in press) [Japanese]
  2. Sunahara T. 2019. Extremely high biting densities of Aedes albopictus (Skuse)(Diptera: Culicidae) at a university campus in Nagasaki, Japan. Japanese Journal of Infectious Diseases (in press)
  3. Imanishi N, Higa Y, Teng HJ, Sunahara T, Minakawa N. 2018. Identification of Three Distinct Groups of  in Japan by Morphological and Genetic Analyses. Japanese Journal of Infectious Diseases 71(6): 427-435.
  4. Sunahara T 2018. Simulation Study of the Effects of Host Availability on Bite Rate of Aedes albopictus (Skuse) (Diptera: Culicidae) and Risk of Dengue Outbreaks in Non-Endemic Areas. Japanese Journal of Infectious Diseases 71(1): 28-32.
  5. Chadeka EA, Nagi S, Sunahara T, Cheruiyot NB, Bahati F, Ozeki Y, Inoue M, Osada-Oka M, Okabe M, Hirayama Y, Changoma M, Adachi K, Mwende F, Kikuchi M, Nakamura R, Kalenda YDJ, Kaneko S, Hirayama K, Shimada M, Ichinose Y, Njenga SM, Matsumoto S, Hamano S. 2017. Spatial distribution and risk factors of Schistosoma haematobium and hookworm infections among schoolchildren in Kwale, Kenya. PLoS Neglected Tropical Disieses 11(9): e0005872

メッセージ

自分の興味に関係する過去の論文を読んで学問的な背景を把握して、重要なのにまだ明らかになっていないことを明確にしてそれをResearch Questionとして具体的な研究方法を考えられれば、研究の70%は完成していると思います。実際に実験や調査を始める前の準備段階を大切にしましょう。

樋泉 道子 助教

    修了課程: 修了年度:

取得学位・資格

  • MD
  • MTM
  • PhD

個人/所属ウェブページ

http://www.tm.nagasaki-u.ac.jp/pediatric/

他所属

Department of Pediatric Infectious Diseases, Institute of Tropical Medicine (NEKKEN), Nagasaki University

経歴

I graduated from Kumamoto University Medical School, Japan and then had worked as a pediatrician for 8 years. Following that, I had studied tropical medicine and pediatric infectious diseases in the Master course of Tropical Medicine and in the Doctoral course in Graduate School of Biomedical Sciences, Nagasaki University. After I received my PhD, I joined the Department of Pediatric Infectious Diseases, the Institute of Tropical Medicine, Nagasaki University as an assistant professor in 2015.

教育活動

Facilitator of Epidemiology-Statistics Course in School of Tropical Medicine and Global Health, Nagasaki University

研究活動

Studies on pediatric infectious diseases in Vietnam:
Acute respiratory infections (incidence, viral/bacterial pathogens, risk factors)
Congenital infections (e.g.,rubella, CMV, Zika) and the effect on child development
Pneumococcal conjugate vaccine reduced dosing trial

現在の主な研究活動地域

ベトナム

最近の5つの出版物

  1. Michiko Toizumi, Motoi Suzuki, Hien Anh Thi Nguyen, Minh Nhat Le, Koya Ariyoshi, Hiroyuki Moriuchi, Masahiro Hashizume, Duc Anh Dang, and Lay-Myint Yoshida
    Viral Acute Respiratory Illnesses in Young Infants Increase the Risk of Respiratory Readmission
    The Pediatric Infectious Disease Journal, in press
  2. Imai, C., Toizumi, M., Hall, L., Lambert, S., Halton, K., Merollini, K.
    A systematic review and meta-analysis of the direct epidemiological and economic effects of seasonal influenza vaccination on healthcare workers
    (2018) PLoS ONE, 13 (6), art. no. e0198685
  3. Toizumi, M., Nguyen, G.T.H., Motomura, H., Nguyen, T.H., Pham, E., Kaneko, K.-I., Uematsu, M., Nguyen, H.A.T., Dang, D.A., Hashizume, M., Yoshida, L.-M., Moriuchi, H.
    Sensory defects and developmental delay among children with congenital rubella syndrome
    (2017) Scientific Reports, 7, art. no. 46483.
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017447271&doi=10.1038%2fsrep46483&partnerID=40&md5=e4958d50959615e2658576c987ed1bc9
    DOI: 10.1038/srep46483
  4. Yoshihara, K., Le, M.N., Okamoto, M., Wadagni, A.C.A., Nguyen, H.A., Toizumi, M., Pham, E., Suzuki, M., Nguyen, A.T.T., Oshitani, H., Ariyoshi, K., Moriuchi, H., Hashizume, M., Dang, D.A., Yoshida, L.-M.
    Association of RSV-A ON1 genotype with Increased Pediatric Acute Lower Respiratory Tract Infection in Vietnam
    (2016) Scientific Reports, 6, art. no. 27856.
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-84975155668&doi=10.1038%2fsrep27856&partnerID=40&md5=762505b0e9f3febd2b4412a119cb6ba8
    DOI: 10.1038/srep27856
  5. Yamanashi, H., Ngoc, M.Q., Van Huy, T., Suzuki, M., Tsujino, A., Toizumi, M., Takahashi, K., Thiem, V.D., Anh, D.D., Anh, N.T.H., Tho, L.H., Maeda, T., Cox, S.E., Yoshida, L.-M., Ariyoshi, K.
    Population-based incidence rates of first-ever stroke in central Vietnam
    (2016) PLoS ONE, 11 (8), art. no. e0160665.
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983475347&doi=10.1371%2fjournal.pone.0160665&partnerID=40&md5=ffb48a6308a404bd39460f8ddd42f7ab
    DOI: 10.1371/journal.pone.0160665

メッセージ

Please join us if you are interested in our researches on pediatric infectious diseases!

Bhim Gopal Dhoubhadel 助教

    修了課程: 修了年度:

取得学位・資格

MBBS, MTM, PhD

ResearchGate/LinkedInアカウント

Twitterアカウント

https://twitter.com/bhim_gopal

経歴

I received my medical degree from BP Koirala Institute of Health Sciences (BPKIHS), Nepal in 2005 and then worked for three years in paediatric hospitals in Nepal followed by one year in a refugee camp for Somali and Ethiopian refugees under UNHCR in Djibouti. Between 2010-11, I completed the Master of Tropical Medicine (MTM) programme in the Institute of Tropical Medicine, Nagasaki University and then a PhD in the Department of Clinical Medicine of the same institute between 2011 and 2014. In 2014, I was a Fellow of the Global (Health) Leadership Program at the University of Tokyo and completed an internship at the headquarters of the World Health Organization (WHO) in Geneva. My research interests are infectious diseases, child health and development of new diagnostic assays. In 2014, we established a new diagnostic assay for serotyping the pneumococcus (a major cause of pneumonia). The assay can identify vaccine serotypes easily and conveniently at a relatively low cost and has been applied in studies in Japan, Vietnam and Afghanistan.

教育活動

At TMGH, I teach master students about essential skills and tropical medicine (clinical bacteriology and molecular diagnostic technique), and organize and facilitate clinical case discussion between the students and doctors in San Lazaro Hospital (Philippians), Bach Mai Hospital (Vietnam) and National Center for Global Health and Medicine (Japan).

Previously I taught advanced paediatric life support (APLS) course to junior medical doctors in Siddhartha Children and Women Hospital, Nepal and child health and management of malnutrition to medical and nursing staffs in Djibouti.

研究活動

I have studied the distribution of pneumococcal serotypes in hospital admitted children and adults in Japan, Vietnam and Afghanistan with a particular focus on the estimation of pneumococcal vaccine coverage.

After I participated in relief efforts following the earthquake in 2015 in Nepal, we are developing a research collaboration with Siddhi Memorial Hospital, Bhaktapur (http://smf.org.np). The focus is on childhood infectious diseases and malnutrition. We are supporting hospital disease surveillance and have conducted nutritional assessments of children who were displaced by the earthquake and living under temporary shelters.

At TMGH, we are establishing new diagnostic assays for typhoid fever based on real-time PCR and loop-mediated isothermal amplification (LAMP). We plan to evaluate these assays in Nepal and other field sites.

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Picture1:Disease surveillance in Siddhi Memorial Hospital, Bhaktapur, Nepal.


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Picture 2: Nutritional assessment of children in temporary shelters in Bhaktapur after 2015 earthquake in Nepal.


現在の主な研究活動地域

  • Japan
  • Nepal
  • Afghanistan

最近の5つの出版物

  1. Kakiuchi S, Suzuki M, Dhoubhadel BG, Furumoto A, Ito H, Kei Matsuki, Tsuchihashi Y, Asoh N, Yasunami M, Ariyoshi K, Morimoto K, Adult Pneumonia Study Group-Japan (2018). Accuracy of high-throughput nanofluidic PCR-based pneumococcal serotyping and quantification assays using sputum samples for diagnosing vaccine serotype pneumococcal pneumonia: analyses by composite diagnostic standards and Bayesian latent class models, J Clin Microbiol.
  2. Shrestha D, Dhoubhadel BG, Parry CM, Prajapati B, Ariyoshi K, Mahaseth C (2017). Predicting deaths in a resource-limited neonatal intensive care unit in Nepal, Trans R Soc Trop Med Hyg.
  3. Zabihullah R, Dhoubhadel BG, Rauf RA, Shafiq SA, Suzuki M, Watanabe K, Yoshida LM, Yasunami M, Zabihullah S, Parry CM, Mirwais R, Ariyoshi K (2017). Risk for death among children with pneumonia, Afghanistan, Emerg Infect Dis.
  4. Suzuki M, Dhoubhadel BG, Ishifuji T, Yasunami M, Yaegashi M, Asoh N, Ishida M, Hamaguchi S, Aoshima M, Ariyoshi K, Morimoto K; Adult Pneumonia Study Group-Japan (APSG-J) (2016). Serotype-specific effectiveness of the 23-valent pneumococcal polysaccharide vaccine against pneumococcal pneumonia among adults aged ≥65 years: a multicenter prospective test-negative design study, Lancet Infect Dis.
  5. Dhoubhadel BG, Yasunami M, Nguyen HA, Suzuki M, Vu TH, Thi Thuy Nguyen A, Dang DA, Yoshida LM, Ariyoshi K (2014) Bacterial Load of Pneumococcal Serotypes Correlates with Their Prevalence and Multiple Serotypes is Associated with Acute Respiratory Infections, PLoS One.

すべての出版物へのリンク

http://www.ncbi.nlm.nih.gov/sites/myncbi/1pMFjL8tdMn55/bibliography/40287257/public/?sort=date&direction=ascending

メッセージ

Clinical infectious diseases, child health and vaccination are some of the inter-related exciting fields of global health.
We have been working in these areas and found that there are lots to discover, learn and contribute on these topics globally.
We hope you will find them interesting and contribute while you study here at TMGH. Welcome!

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