お知らせ

過去の記事一覧

北 潔教授・研究科長

    修了課程: 修了年度:

取得学位・資格

薬学博士(東京大学)・薬剤師

個人/所属ウェブページ

http://www.tmgh.nagasaki-u.ac.jp/about_tmgh/dean

経歴

昭和49年東京大学薬学部卒業後、同薬学系研究科博士課程を修了。東京大学理学部助手、順天堂大学医学部助手、講師を経て、平成3年より東京大学医科学研究所助教授。平成10年より東京大学大学院医学系研究科・教授。平成15~18年、日本寄生虫学会理事長、平成21〜23年、日本生化学会会長。平成24〜27年、東京大学大学院医学系研究科副研究科長。平成27年〜、長崎大学大学院熱帯医学・グローバルヘルス研究科長(平成27年は東京大学と長崎大学のクロスアポイントメント)

教育活動

長崎大学および他大学の学部・大学院にて代謝生化学、分子寄生虫学、創薬学を講義

研究活動

病原体の代謝化学とこれを標的とした創薬

現在の主な研究活動地域

日本、中南米、東南アジア、アフリカ、欧米

最近の5つの出版物

  1. In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease. Yoshino, R., Yasuo, N., Hagiwara, Y., Ishida, T., Inaoka, D.K., Amano, Y., Tateishi, Y., Ohno, K., Namatame, I., Niimi, T., Orita, M., Kita, K., Akiyama, Y. & Sekijima, M. (2017) Sci. Rep. 7, 6666
  2. Expression, purification, and crystallization of type 1 isocitrate dehydrogenase from Trypanosoma brucei brucei. Wang, X., Inaoka, D.K., Shiba T., Balogun, E.O., Allmann, S., Watanabe, Y., Boshart, M., Kita, K. & Harada, S. (2017) Protein Expr. Purif. 138, 56-62
  3. Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity. Balogun, E.O., Inaoka, D.K., Shiba, T., Tokuoka, S.M., Tokumasu, F., Sakamoto, K., Kido, Y., Michels, P.A.M., Watanabe, Y., Harada, S. & Kita K.
    (2017) Biochim. Biophys. Acta (General Subjects) 1861, 2830-2842
  4. Biochemical studies of membrane bound Plasmodium falciparum mitochondrial L-malate:quinone oxidoreductase, a potential drug target. Hartuti, E.D., Inaoka, D.K., Komatsuya, K., Miyazaki, Y., Miller, R.J., Xinying, W., Sadikin, M., Prabandari, E.E., Waluyo, D., Kuroda, M., Amalia, E., Matsuo, Y., Nugroho, N.B., Saimoto, H., Pramisandi, A., Watanabe, Y., Mori, M., Shiomi, K., Balogun, E.O., Shiba, T., Harada, S., Nozaki, T. & Kita K. (2018) Biochim. Biophys. Acta (Biogentics) 1859, 191-200.
  5. Ubiquinone binding site of yeast NADH dehydrogenase revealed by structures binding novel competitive- and mixed-type inhibitors. Yamashita, T., Inaoka, D.K., Shiba, T., Oohashi, T., Iwata, S., Yagi, T., Kosaka, H., Miyoshi, H., Harada, S., Kita, K. & Hirano, K. (2018) Sci. Rep. 8, 2427

メッセージ

日本の基礎研究の成果を世界の人々の健康と幸せのために。

相賀 裕嗣 教授

    修了課程: 修了年度:

取得学位・資格

工学士、保健学修士、保健学博士

ResearchGate/LinkedInアカウント

Research Gate: https://www.researchgate.net/profile/Hirotsugu_Aiga
Publons: https://publons.com/researcher/500515/hirotsugu-aiga/
LinkedIn: https://www.linkedin.com/in/hirotsugu-aiga-86832420/

他所属

School of Tropical Medicine and Global Health, Nagasaki University
NEKKEN, Institute of Tropical Medicine, Nagasaki University

経歴

Education

  • PhD. The University of Tokyo (Human Resources for Health), Tokyo, JAPAN.
  • MSc. The University of Tokyo (Environmental Health), Tokyo, JAPAN.
  • M.Eng. (ABD) Waseda University (Inorganic polymer chemistry), Tokyo, JAPAN.
  • B.Eng. Waseda University (Functional polymer chemistry), Tokyo, JAPAN.

Professions

  • Japan International Cooperation Agency (JICA), Senior Adviser on Health and Nutrition, Tokyo, JAPAN.
  • Ministry of Health, Maternal & Child Health Dept, Chief Adviser for MCH Project, Hanoi, VIETNAM.
  • World Health Organization (WHO), HIV/AIDS Dept, Senior Epidemiologist, Geneva, SWITZERLAND.
  • World Health Organization (WHO), Global Health Workforce Alliance, Coordinator, Geneva, SWITZERLAND.
  • World Food Programme (WFP), Emergency Food Security Assessment Services, Senior Programme Adviser, Rome, ITALY.
  • The George Washington University (GWU), School of Public Health & Health Services, Adjunct Professor, Washington DC, USA.
  • Ministry of Health, Human Resource Development Specialist for HRH Project, Accra, GHANA.
  • Engineering Consulting Firms Association (ECFA), Research Division, Director & Principal Researcher, Tokyo, JAPAN.
  • International Federation of Red Cross & Red Crescent Societies (IFRC), Russian Far-East Delegation, Regional Logistic & Relief Delegate, Khabarovsk, RUSSIAN FEDERATION.
  • International Federation of Red Cross & Red Crescent Societies (IFRC), Central Asian Regional Delegation, Regional Logistic & Relief Delegate, Almaty, KAZAKHSTAN.
  • World Health Organization (WHO), Western Pacific Regional Office, Environmental Health Division, Research Officer, Manila, THE PHILIPPINES.
  • Zorzor Rural Teachers Training Institute (ZRTTI), Science Dept, Chair, Fissebu, LIBERIA.
  • Tokyo Metropolitan Government, Public High Schools, Science Teacher, Tokyo, JAPAN.

教育活動

  • Kitasato University, School of Medical Sciences, Sagamihara, JAPAN (Global health).
  • The University of Tokyo, School of International Health, Tokyo, JAPAN (Global health).
  • University of Geneva, School of Medicine, Geneva, SWITZERLAND (Health workforce development).
  • The George Washington University (GWU), Washington DC, USA (Global health and health system).
  • Yokohama National University, School of International Social Sciences, Yokohama, JAPAN (International development).
  • Tokyo University of Agriculture and Technology, School of Agriculture, Tokyo, JAPAN (Food security policy).
  • Zorzor Rural Teachers Training Institute (ZRTTI), Fissebu, LIBERIA (Calculus, chemistry, physics and child development).
  • Japanese School of Accra, Accra, GHANA (Mathematics).
  • Sunagawa Public High School, Tokyo, JAPAN (Chemistry and general science).
  • Shinozaki Public High School, Tokyo, JAPAN (Chemistry).

研究活動

  • Health workforce development: Specialized in policy analysis on health workforce development. Managed, supervised, and advised on national health workforce policies and systems in Cambodia, DRC, Fiji, Ghana, Tonga, Vietnam and Vanuatu.
  • Household food security and nutrition: Specialized in household food security measurement and nutrition surveys. Contributed to development of international guidelines for food security estimation. Designed, managed and conducted food security, nutrition, and mortality surveys in DRC, India, Liberia, Madagascar, Malawi, Mozambique and Sudan.
  • Epidemiology of infectious diseases: Specialized in epidemiology of diarrheal diseases and Neglected Tropical Diseases (e.g. Chagas disease and Buruli ulcer). Conducted epidemiologic studies in El Salvador, Ghana, Honduras and the Philippines.
  • Maternal and child health: Specialized in home-based records (HBRs) for maternal and child health. Estimated the impact of HBRs on health seeking behaviors in Angola, Mozambique and Vietnam and conducted a review on HBR implementation realities.
  • Health information systems: Specialized in both population-based and facility-based health information systems (HISs). Managed, supervised and advised on health management information systems (HMISs) and disease-specific information/surveillance systems in Ethiopia, Guatemala, Indonesia, Pakistan and South Africa.

現在の主な研究活動地域

  • Angola
  • Cambodia
  • Kenya
  • Mozambique
  • Nigeria
  • Tanzania
  • Vietnam
  • Zambia

最近の5つの出版物

  • Aiga H (2020) Adapting health workforce density threshold to WHO new antenatal care guidelines. Lancet. 395 (10217) 27.
  • Aiga H, Abe K, Andrianome VN, Randriamampionona E, Razafinombana RA, Murai T, Hara M. (2019) Risk factors for malnutrition among school-aged children: A cross-sectional study in rural Madagascar. BMC Public Health. 19 (1): 773.
  • Osaki K, Aiga H. (2019) Adapting home-based records for maternal and child health to uses’ capacities. Bull World Health Organ. 97 (4): 296-305.
  • Aiga H, Nguyen DV, Nguyen DC, Nguyen TTT, Nguyen TPL. (2016) Fragmented implementations of maternal and child health home-based records in Vietnam: Need for an integration. Global Health Action 9 (2):29924.
  • Aiga H. (2015) Hidden out-of-pocket payments can burden patients’ families but are under-recognised. BMJ. 351. H4990.

メッセージ

Having been bearing global health as one of practical sciences in mind, I worked at a variety of organizations both as a practitioner and as a researcher. Throughout my professional career, I have learned that practicing and researching are key two wheels of a vehicle that takes us to healthier and more productive world. My research interests are diverse, yet likely focused more on health system strengthening. I look forward to doing research with you not only on important global health agenda but also on neglected global health issues, for identifying their effective and feasible solutions in an evidenced-based manner.

有吉 紅也 教授

    修了課程: 修了年度:

取得学位・資格

M.D.(Japan), DTM&H (London), MSc Clinical Tropical Medicine (London), PhD (U.K.)

個人/所属ウェブページ

http://www.tm.nagasaki-u.ac.jp/internal/nekkennaika.htm

連絡先

kari@nagasaki-u.ac.jp

他所属

  • Department of Clinical Medicine, Institute of Tropical Medicine (NEKKEN)
  • Department of Infectious Diseases, Nagasaki University Hospital
  • School of Tropical Medicine and Global Health, Nagasaki University
  • Honorary Professor, Clinical Research Department, Faculty of Infectious Tropical Medicine, London School of Tropical Medicine and Hygiene, UK

経歴

I had my residency training in internal medicine in Tokyo, 1986-1988. From those days I was interested in working in Africa, which let me do DTMH in London, followed by a post-graduate clinical training in Harare Central Hospital, Zimbabwe, 1989 where I encountered my life work, AIDS. My master project on HIV viral load at LSHTM in 1990 was very successful that I was offered a job as a clinical research fellow at the Jefferiss Wing, St. Mary’s Hospital. My asset of multi-disciplinary human-network has been established when working in London, Oxford and West Africa for 8 years as well as in Tokyo at NIID for 3 years and in Thailand for JICA for 4 years.

教育活動

I am the course director of Master of Tropical Medicine (MTM) where I teach clinical tropical medicine, malaria and non-malaria febrile illness, STD and HIV/AIDS. I also facilitate the tropical infectious disease case discussion.

As a chief of NEKKEN training/education center, I also organize the three-month diploma course of tropical medicine.

研究活動

HIV research had been a core of my carrier before joining NEKKEN. It broadened my skills to understand a disease from multidisciplinary aspects such as behavioral, epidemiological, clinical science, molecular immunology and virology. Most of my work has derived from clinical-epidemiology settings such as cohort or case-control studies. I enjoy digging out clinical research questions by seeing patients and discussing with medical professionals. On joining to the current group of NEKKEN, my research topic has been broaden toward pneumonia in low, middle and high-income countries, non-malarial febrile illness such as typhus, leptospirosis. Now we have on-going studies in infectious disease wards in North Vietnam, the Philippines and Japan.
ariyoshi_koya_document01Discussing in an overcrowded ward in Bac Mai Hospital, Vietnam with Dr. Thuy, one of the most experienced I.D. physicians.

現在の主な研究活動地域

  • The Philippines
  • Vietnam
  • Thailand
  • Japan

最近の5つの出版物

Hyperlink to the NAOSITE of each paper will be posted if it is “open access”, so that viewers can jump straight to the text of the paper.

  1. Kitashoji E, Koizumi N, Lacuesta TLV, Usuda D, Ribo MR, Tria ES, Go WS, Kojiro M, Parry CM, Dimaano EM, Villarama JB, Ohnishi M, Suzuki M, Ariyoshi K. Diagnostic Accuracy of Recombinant immunoglobulin-like Protein A-Based IgM ELISA for the Early Diagnosis of Leptospirosis in the Philippines. PLoS Negl Trop Dis 9(6): e0003879.(2015)
  2. Morimoto K, Suzuki M, Ishifuji T, Yaegashi M, Asoh N, Hamashige N, Abe M, Aoshima M, Ariyoshi K; Adult Pneumonia Study Group-Japan (APSG-J). The burden and etiology of community-onset pneumonia in the aging Japanese population: a multicenter prospective study. PLoS One. 10(3): e0122247.(2015)
  3. Hamaguchi S, Cuong NC, Tra DT, Doan YH, Shimizu K, Tuan NQ, Yoshida LM, Mai LQ, Duc-Anh D, Ando S, Arikawa J, Parry CM, Ariyoshi K, Thuy PT. Clinical and Epidemiological Characteristics of Scrub Typhus and Murine Typhus Among Hospitalized Patients with Acute Undifferentiated Fever in Northern Vietnam. Am J Trop Med Hyg. pii: 14-0806.(2015)
  4. Dhoubhadel BG, Yasunami M, Nguyen HA, Suzuki M, Vu TH, Thi Thuy Nguyen A, Dang DA, Yoshida LM, Ariyoshi K. Bacterial load of pneumococcal serotypes correlates with their prevalence and multiple serotypes is associated with acute respiratory infections among children less than 5 years of age. PLoS One. 31;9(10):e110777.(2014)
  5. M Mori, N Wichukchinda, R Miyahara, A Rojanawiwat, P Pathipvanich, T Maekawa, T Miura, P Goulder, M Yasunami, K Ariyoshi, P. Sawanpanyalert. HLA-B*35:05 is a protective allele with a unique structure amongst HIV-1 CRF01_AE-infected Thais, where the B*57 frequency is low. AIDS ; 28(7): 959-67.(2014)

他の出版物へのリンク

http://www.ncbi.nlm.nih.gov/sites/myncbi/1n5JSXaavr65l/bibliography/48630402/public/?sort=date&direction=ascending

メッセージ

1992年より6年間,英国MRCガンビア研究所でエイズ研究と研究所附属病院での臨床を経験,このときの国際的人脈が財産。帰国後は4年間タイに滞在し,タイ人エイズ研究者の育成に努めた。2005年長崎大学教授就任後は,主にベトナム,フィリピンでの臨床疫学研究を推進しつつ,長崎大学病院では感染症内科(熱研内科)科長として内科診療に従事。また,熱研教育室長,長崎大学熱帯医学・グローバルヘルス研究科副研究科長として熱帯医学教育に広く携わる。日本よりはるかに難しい課題を抱えた途上国の医療保健現場で役に立ちたいと思うのなら,さらに努力して勉強する気概をもって欲しい。

奥村 順子 教授

    修了課程: 修了年度:

取得学位・資格

Pharmacist, MPH (U of Michigan), PhD

ResearchGate/LinkedInアカウント

http://www.researchgate.net/profile/Junko_Okumura

他所属

Nagasaki University, Institute of Tropical Medicine (Main work station).

教育活動

Please refer the TMGH Syllabus.

研究活動

Will be filled later

現在の主な研究活動地域

  • Will be filled later
    You might also consider using a PubMed Bibliography Collection as it can be used to easily keep your publications up to date and provide a list of publication references, for example, for your CV or as a web link – please see below.
  • Please refer 6. Research gate.

メッセージ

「何もしなかった」と後で悩みたくはなかった私は,思いつくままに海外の現場で働く中で,己の無知を知り,37歳を過ぎて大学院で学び始めました。その後,かなり遅咲きの研究者になり,日夜溺れるほどの情報の中で未だに「無知の知」を認識する日々です。「やらなければよかった」という後悔と,「やればよかった」という後悔・・・。どちらを選ぶかはあなた次第です。開発であれ,国際保健であれ,あなたの求める答えは,あなた自身で見つけるしかありません。教科書や講義は,そのヒントを与えるものに過ぎないでしょう。

金子 聰 教授

    修了課程: 修了年度:

取得学位・資格

M.D.,M.P.H.,Ph.D

個人/所属ウェブページ

他所属

  • Institute of Tropical Medicine, Nagasaki University
  • Visiting lecturer of Tohoku University
  • Visiting scientist of Osaka Kyoiku University

Other titles

  • Associate Editor of Journal of Epidemiology
  • Councilor of Japanese Society of Tropical Medicine
  • JICA Consultant, Sri Lanka Non-communicable disease management project

経歴

  • Graduated from the National Defense Medical College, Saitama, Japan in 1990
  • JICA expert in the Tropical Disease Control Project for Chagas disease in Guatemala in 1995
  • Master of Public Health (MPH) degree from Harvard School of Public Health, Boston, Massachusetts, U.S.A in 1997.
  • PhD degree from the Graduate School of Medical Science, University of Occupational and Environmental Health, JAPAN (UOEH), Kitakyushu, JAPAN in 2001
  • Head of Cancer Surveillance Section, Statistics and Cancer Control Division in National Cancer Center, Tokyo from 2001 until 2005
  • Professor (Fixed-term) at Institute of Tropical Medicine, Nagasaki University since 2005 to present (Between 2006 and 2010, appointed at Nairobi Research Station, Nagasaki University)
  • Professor at Nagasaki University Graduate School of International Health Development since 2008 to present

教育活動

  • Professor (Fixed-term) at Institute of Tropical Medicine, Nagasaki University since 2005 to present (Between 2006 and 2010, appointed at Nairobi Research Station, Nagasaki University)
  • Professor at Nagasaki University Graduate School of International Health Development since 2008 to present

研究活動

  • Development of microsphere-based simultaneous multiple assays and surveillance systems for multiple infectious diseases in Africa.
  • Health and Demographic Surveillance System (HDSS) in Lao PDR.
  • Epidemiological studies for child health in Kenya.
  • Research on dengue prevention through a residential environmental clean-up program in Sri Lanka.
  • Finding malaria vaccine candidate antigens using microsphere-based simultaneous multiple assays.
  • A scientific approach to community-led total sanitation strategies in Africa.
  • Non-communicable disease (NCD) project by JICA in Sri Lanka.
  • Developing epidemiological data-collection tools using the cutting edge IT technology to monitor health-related problems in developing world; e.g., biometrics (vein authentication) to identify people and link different data sources (link: here)

現在の主な研究活動地域

  • Africa
  • Asia

最近の5つの出版物

  1. Shinsugi C, Matsumura M, Karama M, Tanaka J, Changoma M, Kaneko S. Factors associated with stunting among children according to the level of food insecurity in the household: a cross-sectional study in a rural community of Southeastern Kenya. BMC public health 2015; 15(1): 441-51.(2015)
  2. Fujii Y, Kaneko S, Nzou SM, Mwau M, Njenga SM, Tanigawa C, Kimotho J, Mwangi AW, Kiche I, Matsumoto S, Niki M, Osada-Oka M, Ichinose Y, Inoue M, Itoh M, Tachibana H, Ishii K, Tsuboi T, Yoshida LM, Mondal D, Haque R, Hamano S, Changoma M, Hoshi T, Kamo K, Karama M, Miura M, Hirayama K. Serological surveillance development for tropical infectious diseases using simultaneous microsphere-based multiplex assays and finite mixture models. PLoS neglected tropical diseases 2014 Jul; 8(7): e3040.(2014)
  3. Miura M, Tanigawa C, Fujii Y, Kaneko S. Comparison of six commercially-available DNA polymerases for direct PCR. Rev Inst Med Trop Sao Paulo 2013 Nov-Dec; 55(6): 401-6.(2013)
  4. Kaneko S, K’Opiyo J, Kiche I, Wanyua S, Goto K, Tanaka J, Changoma M, Ndemwa M, Komazawa O, Karama M, Moji K, Shimada M. Health and Demographic Surveillance System in the Western and Coastal Areas of Kenya: An Infrastructure for Epidemiologic Studies in Africa. J Epidemiol 2012 Feb 25; 22(3): 276-85.(2012)
  5. Komazawa O, Kaneko S, K’Opiyo J, Kiche I, Wanyua S, Shimada M, Karama M. Are Long-Lasting Insecticidal Nets Effective for Preventing Childhood Deaths among Non-Net Users? A Community-Based Cohort Study in Western Kenya. PloS one 2012; 7(11): e49604.(2012)

メッセージ

現場から学ぶ。そこからすべてが始まります。何が問題なのか?解決するためには何が必要なのか?そのためには,“知識”と”ツール“が必要です。そして,それらを真摯な姿勢で観察し,科学的に解明しようとする姿勢。現在われわれの抱えている多くの問題には,用意された解答はありません。本研究科では,「”現場“から”アカデミックの場“へ,そして”アカデミックの場“から”現場“へ」を目指しています。ともに,学び,実践し,さらに研究へと展開させ,そして実践に帰る。一緒に未知の世界を目指してみませんか?

神谷 保彦教授

    修了課程: 修了年度:

取得学位・資格

M.D., M.Trop.Paed., PhD

ResearchGate/LinkedInアカウント

https://www.researchgate.net/profile/Yasuhiko_Kamiya

他所属

  • Graduate School of Tropical Medicine & Global Health, Nagasaki University, Japan
  • Nagasaki University Graduate School of Biomedical Sciences

経歴

After acquiring MD. from Kochi Medical School in 1985, I worked for children with disability. I acquired Masters in Tropical Paediatrics from Liverpool School of Tropical Medicine in 1995, with the dissertation “ Pneumocystis Pneumonia in HIV infected children in Malawi”, and Ph.D. from Faculty of Medicine, University of Liverpool in 2002 with the thesis “Epidemiology and microbiology of acute respiratory infections in children in an urban poor area in Nairobi, Kenya and molecular epidemiology of RS virus”. I joined vaccine trials for pertussis and measles in Ghana. I worked for humanitarian assistance in the former Yugoslavia, the former Zaire, Iraq, Afghanistan, Honduras and South Sudan with AMDA, Peace Wind Japan, UNHCR, and UNICEF. I have consulted and coordinated on community health, health system strengthening, epidemiology on infectious diseases and NCD in Sri Lanka, Kenya, Ghana, Fiji and Philippines and for local capacity development for health system research and epidemiology.

教育活動

I will be teaching Global Health I, Child Health I, Child Health II, Community Health I, and Emergency Assistance I at the TMGH, and also supervising Long Term Internship for MPH course. Currently I am teaching child health and pediatric diseases in MTM and TTM courses, and current epidemiological transition and health system research at the phD Leading program. Previously I taught Overview of Global Health, Child Health, and Emergency Assistance at the Graduate School of International Health Development, along with supervision for long term internship for MPH students.

研究活動

I have been studying aid effectiveness, particularly on aid fragmentation and its effect on health system. I participated in randomized control trials for several vaccines in Ghana, and did clinical and microbiological (molecular biological) study on RS virus and pneumocystis pneumonia in Malawi, cohort study for ARI in children in Kenya and NCD especially cardiovascular diseases and diabetes in Sri Lanka as well as research on referral system in Ghana, and supervision and health information system in Kenya along with overuse of antibiotics, disease replacement under polymicrobial status. I am also engaged in study on access and seeking behavior in children with disability in the Philippines.

現在の主な研究活動地域

  • Japan
  • Ghana
  • Kenya
  • Honduras
  • Philippines
  • Sri Lanka
  • South Sudan
  • India

最近の5つの出版物

  1. Tsukakoshi T, Samuela J, Rafai EV, Rabuatoka U, Honda S, Kamiya Y, Buerano CC, Morita K. Hepatitis B serologic survey and review of immunization cords of children, adolescents and adults in Fiji, 2008–2009. Virology Journal 2015, 12:36
  2. Kamiya Y. Epidemiology of infectious diseases in Africa in relation to polymicrobial replacement, urbanization, and control measures in health systems. Yves Charbit and Teiko Mishima (Eds.), Questions de migrations et de sante en Afrique Sub-saharienne (Issues of Migrations and Health in Sub-Saharan Africa). Recherches interdisciplinaires en France et au Japan. (pp. 187-213) 2014, Paris: L’ Harmattan.
  3. Masumoto S, Yamamoto T, Ohkado A, Yoshimatsu S, Querri AG, Kamiya Y. Prevalence and associated factors of depressive state among pulmonary tuberculosis patients in Manila, the Philippines. International Journal of Tubercle and Lung Disease. 2014. 18 (2) 174-179.
  4. Masumoto S, Yamamoto T, Ohkado A, Yoshimatsu S, Querri AG, Kamiya Y.. Factors associated with health-related quality of life among pulmonary tuberculosis patients in Manila, the Philippines. Quality of Life Research 2014 Jun;23(5):1523-1533.
  5. Sasaki E, Kamiya Y*. Caregivers’ Understanding of Pediatric Medication in Central Malawi. J Trop Pediatr. doi: 10.1093/tropej/fmu057 2014.

メッセージ

開発援助では,介入の度合いや支援の仕方など自分の位置取りを問われ,緊急人道援助では難しい即断を迫られますが,やればやるほど国際協力の形骸化や限界,理想と現実とのギャップに,そして,現場の人たちから学ぶことが多いと,気が付くのは自明です。自身のキャリアアップに囚われず,現地の人々と共にケイパビリティ(潜在能力)を拡げるためには,学ぶだけでなく,un-learning学び捨てることも必要です。教室で教え,学ぶ事と現場で実際に起こっている事,やっている事の間には常にズレがあります。自分たちの現場での失敗や反省を教員と学生が共有し合うことが,学生の資格や教員のポストのためでなく,援助を受ける人たちのためになると確信します。本コースが,教える,学ぶことの特権性を自覚し合い,複眼的思考をもつ自己批判精神の旺盛な人材へと常に生成する場の一つになればと思います。

Christopher Smith 教授

    修了課程: 修了年度:

取得学位・資格

MRCP, MRCGP, MSc, PhD, DTM&H (東アフリカパートナーシップ)

個人/所属ウェブページ

https://www.lshtm.ac.uk/aboutus/people/smith.christopher

ResearchGate/LinkedInアカウント

https://www.linkedin.com/in/chris-smith-44580610/

他所属

  • Graduate School of Tropical Medicine and Global Health, Nagasaki University
  • Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine

経歴

2014年より、Medical Research Council(MRC)の人口科学者フェローシップの特別研究員として、LSHTMで働いてきました。2017年9月からは、ロンドン大学衛生・熱帯医学大学院(LSHTM)と長崎大学大学院熱帯医学・グローバルヘルス研究科(TMGH)とのクロスアポイントメントとなり、両大学で研究指導を行っています。私の主な研究分野は、性的及びリプロダクティブ・ヘルスを支えるデジタル・ヘルス・インターベンションに関する分野です。2017年にLSHTMにおいて、カンボジアのマリーストップスインターナショナルと共同で実施した、mHealthサービスによる避妊対策の系統的レビュー、および家族計画改善のために開発されたMObile技術(MOTIF)を用いた博士論文(題目:‘Increasing contraception use with mobile phone-based interventions’「携帯電話ベースのヘルスケアサービスによる避妊薬の使用を増やす対策」により、学位を取得しました。2010年から2012年までインペリアルカレッジロンドンを拠点とする国立健康研究所(NIHR)のフェローシップの一環として、2011年にLSHTMの博士前期課程開発途上国における公衆衛生学(MSc)を修了しました。

ロンドンで総合診療医(GP)として働き、カンボジアにてMaddox Jolie-Pitt基金によるNHSプロジェクトとウガンダで国境なき医師団(Medecins Sans Frontieres)の一員としてプロジェクトに従事しました。

教育活動

過去3年間にわたり、LSHTMにおけるファミリープランニングプログラムモジュール(2401)を担当し、現在は長崎大学を拠点とし、博士前期課程および博士後期課程の学生を指導しています。

研究活動

携帯電話による介入(デジタル/ mHealth)、性的及びリプロダクティブ・ヘルス、一次医療(プライマリケア)、 ヘルスパートナーシップの研究を行っています。AHRCからの資金交付により、SOAS、キングズ・カレッジ・ロンドン、マリー・ストップズ・インターナショナルの共同研究者とともに、カンボジアにおけるリプロダクティブ・ヘルスを向上するためのプロジェクトに主任研究員として携わっています。以下の出版リストに加えて、厳選された出版物は下記リンクより閲覧できます。https://www.ncbi.nlm.nih.gov/pubmed/?cmd=historysearch&querykey=1

詳しい情報または研究や博士後期課程に関するプロジェクトについて相談したい方は、ご連絡して下さい。

現在の主な研究活動地域

  • 日本
  • イギリス
  • カンボジア
  • フィリピン

最近の5つの出版物

  1. Kuhlin J, Smith C, Khaemraev A, Tigay Z, Parpieva N, Tillyashaykhov M, Achar J, Hajek J, Greig J, du Cros P, Moore D. The impact of pyrazinamide resistance on multidrug-resistant tuberculosis in Karakalpakstan, Uzbekistan. The International Journal of Tuberculosis and Lung Disease. 2018;22(5):544-550
  2. Smith C, Edwards P, Free C. Assessing the validity and reliability of self-report data on contraception use in the Mobile Technology for Improved Family Planning (MOTIF) randomised controlled trial. Reproductive Health. 2018;15:50
  3. Smith C, Ngo T, Gold G, Edwards P, Vannak U, Sokhey L, Machiyama K, Slaymaker E, Warnock R, McCarthy O, Free C. Effect of a mobile phone-based intervention on post-abortion contraception: a randomized controlled trial in Cambodia. Bulletin of the World Health Organization. 2015.
  4. Smith C, Gold J, Ngo T, Sumpter C, Free C. Mobile phone-based interventions for improving contraception use (Review). Cochrane Database Syst Rev. 2015;(6)
  5. Smith C, Pettigrew L, Seo H, Dorwood J. Combining General Practice with International work: experiences of UK GPs. J R Soc Med Sh Rep. 2012;3(46):1-9

メッセージ

私は、混合研究法の経験を有する臨床研究者で、多様な分野に興味を持っています。イギリスとウガンダで総合診療医(GP)として働き、また、ウガンダにおいてProfessional Diploma in Tropical Medicine and Hygiene (DTM&H): East African partnershipを修了しました。主に、カンボジアでのランダム化比較試験を含む、リプロダクティブ・ヘルスに対するデジタル・ヘルスサービスの提供について研究を行ってきました。詳しい情報または研究や博士後期課程に関するプロジェクトについて相談を希望する方はご連絡下さい。

Sharon Cox教授

    修了課程: 修了年度:

取得学位・資格

BSc, MSc, PhD

個人/所属ウェブページ

http://www.lshtm.ac.uk/aboutus/people/cox.sharon

ResearchGate/LinkedInアカウント

https://www.researchgate.net/profile/Sharon_Cox

Twitterアカウント

@sharonecox15

他所属

School of Tropical Medicine and Global Health, Nagasaki University, Japan
London School of Hygiene and Tropical Medicine, London, UK

経歴

I graduated from University College London with a BSc. (Biochemistry, First Class Hons) in 1996, followed by a postgraduate teaching qualification (1997), a Masters in Public Health Nutrition at the London School of Hygiene & Tropical Medicine [LSHTM] (1998) and finally a PhD, also at LSHTM (2003). My PhD comprised a clinical trial of low-dose maternal vitamin A supplementation to determine effects on immunity to malaria in pregnancy in Ghana. In 2002 I became a staff member at LSHTM within the MRC International Nutrition Group and worked on malaria and anemia in Gambian children. In 2007 I moved to be based in Dar es Salaam Tanzania, working mostly on sickle cell disease. In 2015 I was appointed as a Professor at School of Tropical Medicine & Global Health, Nagasaki University, where I am now based. I also hold a joint appointment at LSHTM.

教育活動

I co-organise courses in Epidemiology and Statistics in semesters 1 and 3 for the TMGH MSc courses. These courses are based on those provided by the London School of Hygiene & Tropical Medicine masters programmes and are taught by Nagasaki and visiting LSHTM research staff. I also organise a module on Nutrition for Global Health in Semester 3 and teach individual sessions on in other modules on effects of both under and over-nutrition, diagnosis and management of acute malnutrition, nutrition and infection, causes and effects of anaemia in the tropics, epidemiology and field-based research methodology

Previously at the London School of Hygiene & Tropical Medicine, UK I taught and managed units within the MSc in Public Health Nutrition and I have been a tutor on distance based learning MSc courses: “Nutrition and Infection” & “Study Design: writing a grant application.

研究活動

I am interested in how nutrition underpins human health and in particular in relation to interactions with infections, other conditions like sickle cell disease and maternal and child health. My research aims to provide an evidence base to support nutrition-based interventions to improve health outcomes in populations in low and middle income countries.
Current ongoing studies are summarized below:
Nutrition and TB
I am leading research on nutrition and diabetes in TB patients in the Philippines in both inpatient and outpatient populations in Metro Manila, Cebu and Negros Occidental. I collaborate with investigators from San Lazaro Hospital, Manila, the Nutrition Centre, Philippines and the National TB programme.
Malnutrition in children
In Nepal I am leading research assessing malnutrition in pediatric admissions and outpatient clinics (children of all ages). In Cambodia, we are investigating the determinants of malnutrition of young children within the NHAM birth cohort, with a focus on infections and the microbiome. In Burundi we are collaborating with Action Against Hunger to evaluate malnutrition diagnosis and referral within the integrated community case based management programme (iCCM).
Nutrition as a modulator of sickle cell disease
Within the Muhimbili Sickle Cohort in Tanzania, my previous research has focused on nutritional and genetic modulation of sickle cell disease (SCD).

現在の主な研究活動地域

The Philippines, Nepal, Bangladesh, Cambodia, UK, Japan, Tanzania, Kenya, The Gambia, India

最近の5つの出版物

  1. Lee N, Makani J, Tluway F, Makubi A, Armitage AE, Pasricha SR, Drakesmith A, Prentice AM & Cox SE. Decreased hepcidin levels are associated with low steady-state hemoglobin in children in the Muhimbili sickle cohort, Tanzania. EBioMed, 2018. In press
  2. Cox SE, Ellins EA, Marealle AI, Newton CR, Soka D, Sasi P, Di Tanna GL, Johnson W, Makani J, Prentice AM, Halcox JP & Kirkham FJ. Ready-to-use food supplement +/- arginine & citrulline with daily chloroquine in Tanzanian children with sickle cell disease: a double blind random order cross-over trial. Lancet Hematology, 2018 In press –
  3. Yamanashi H, Kulkarni B, Edwards T, Kinra S, Koyamatsu J, Nagayoshi M, Shimizu Y, Maeda T & Cox SE. Association between atherosclerosis and handgrip strength in non-hypertensive populations in India and Japan. Geriatrics & Gerontology International, in press –
  4. Marealle AI, Siervo M, Wassel S, Bluck L, Prentice AM, Minzi O, Sasi P, Kamuhabwa A, Soka D, Makani J, Cox SE. A pilot study of a non-invasive oral nitrate stable isotopic method suggests that arginine and citrulline supplementation increases whole-body NO production in Tanzanian children with sickle cell disease. Nitric Oxide. 2018 Jan 2;74:19-22. doi: 10.1016/j.niox.2017.12.009. [Epub ahead of print]
  5. Nkya S, Mgaya J, Urio F, Makubi A, Thein SL, Menzel S, Cox SE, Newton CR, Kirkham FJ, Mmbando BP, Makani J. Fetal Hemoglobin is Associated with Peripheral Oxygen Saturation in Sickle Cell Disease in Tanzania. EBioMedicine. 2017 Sep;23:146-149. doi: 10.1016/j.ebiom.2017.08.006. Epub 2017 Aug 8.

他の出版物へのリンク

http://www.ncbi.nlm.nih.gov/sites/myncbi/1tmZEPnoXym/bibliography/40021911/public/?sort=date&direction=decendinga

メッセージ

I propose that nutrition is one of the most important modifiable environmental factors underlying health and disease. Along with infections such as malaria, nutrition has been one of the strongest selection pressures over our recent evolutionary history. This has significant implications in relation to the rapid changes in diet and lifestyle that are occurring globally. Under and over-nutrition are increasingly occurring within the same population groups and in both low and high-income countries.
Nutrition is essential to consider at individual and community/population levels in order to ensure that health interventions are optimally successful.
My research focuses on understanding the mechanisms by which nutritional factors affect health outcomes, with a focus on low- and middle-income country settings and encompassing infectious and non-infectious disease processes.

門司 和彦 教授

    修了課程: 修了年度:

取得学位・資格

PhD (Health Sciences), MSc (Health Sciences)

個人/所属ウェブページ

Old record:http://archives.chikyu.ac.jp/archives/AnnualReport/Viewer.do?prkbn=R&jekbn=E&id=98

ResearchGate/LinkedInアカウント

http://www.researchgate.net/profile/Kazuhiko_Moji

他所属

  • Graduate School of Tropical Medicine & Global Health, Nagasaki University, Japan
  • Institute of Tropical Medicine, Nagasaki University
  • School of Global Humanities and Social Sciences
  • Research Institute for Humanity and Nature (RIHN), Kyoto, Japan: Professor Emeritus

経歴

I graduated from the University of Tokyo (UT) in 1976 (BSc. in Health Sciences) , Then, I was in UT until I am 34 as a research student in the department of human ecology (1976-1978), a master course student (1978-1980), a PhD student (1980-1983), and a research associate (1983-1987). I joined to Nagasaki University in 1987, as an associate professor of public health at School of Medicine, then as a professor of community health at School of Allied Medical Sciences in 1999. From 2002, I moved to Nekken, Institute of Tropical Medicine as a professor at the Research Center for Tropical Infectious Diseases (RECTID). Between 2007 and 2013, I was in Research Institute for Humanity and Nature (RIHN), Kyoto, as a project leader of “The RIHN Ecohealth project: Environmental Change and Infectious Diseases in Tropical Asia. After the RIHN Ecohealth project, I joined again to Nagasaki University, being professor and dean of the graduate school of international health development, which is the precursor of this graduate school of tropical medicine and global health.

教育活動

Based on my back ground of human ecology, I will be teaching various aspects of bio-social approach to global health. Bio-medical science and epidemiology are very important part of global health. Yet, students need to acquire enough knowledge on wider bio-social context of each society which is shaping the health of the people, in order to contribute to the sustainable development goals of global health. Students need to understand people’s life, their environments, their society’s history, culture, social and political system, public health systems and so on. I will teach the following modules: Global Health in the autumn quarter, Health Promotion Ⅰand Ⅱ in the winter quarter. And I will serve as an organizer/coordinator for Health System and Policy Ⅰand Ⅱ, and Social Entrepreneurship.

研究活動

I have been studying human ecology of people living in various environments in Asia, Africa and South America. Based on intensive field work in rural communities, I studied demographic events (death, pregnancy, birth and in/out migration), time-allocation of human activities, their interaction with environment, food acquisition, diet, energy and nutrient intake, and energy output. Then, I started to study health ecology of parasitic diseases such as schistosomiasis haematobium in Kenya, malaria in Indonesia and Lao P.D.R. and liver fluke infection in Lao P.D.R. I have been interested in ecohealth/human ecology approaches (non-pharmaceutical approaches) to reduce the burden of these parasitic diseases and to accelerate health transition.

現在の主な研究活動地域

Currently: Lao P.D.R, and Indonesia
In the past: Japan, Kenya, Bolivia, Bangladesh, China, and Vietnam

最近の5つの出版物

  1. Density dependence in a seasonal time series of the bamboo mosquito, Tripteroides bambusa (Diptera: Culicidae) Hoshi, T., Imanishi, N., Moji, K., Chaves, L.F. 2017 Canadian Entomologist 149(3), pp. 338-344
  2. The role of domestic dogs in the transmission of zoonotic helminthes in a rural area of Mekong river basin Sato, M.O., Sato, M., Yoonuan, T., (…), Moji, K., Waikagul, J. 2017 Acta Parasitologica 62(2), pp. 393-400
  3. Application of environmental DNA analysis for the detection of Opisthorchis viverrini DNA in water samples Hashizume, H., Sato, M., Sato, M.O., (…), Moji, K., Minamoto, T. 2017 Acta Tropica 169, pp. 1-7
  4. Household clustering of asymptomatic malaria infections in Xepon district, Savannakhet province, Lao PDR Pongvongsa, T., Nonaka, D., Iwagami, M., (…), Mita, T., Kano, S. 2016 Malaria Journal 15(1),508
  5. Morbidity assessment of Opisthorchis viverrini infection in rural Laos: I. Parasitological, clinical, ultrasonographical and biochemical findings Feldmeier, H., Hazay, M., Sato, M., (…), Sopraseuth, V., Moji, K. 2016 Tropical Medicine and Health

すべての出版物へのリンク

For other publication

メッセージ

この世の中は矛盾と不条理に満ちています。もし,皆さんがアフリカや熱帯アジアの貧しい家庭に生まれたと想像してみてください。どうやって生き延び,病気から逃れ,何を食べて何をして生きていくことができるでしょうか。学校にも行けず字も読めなければ,どうやって社会からさげすまれずに生きていくことができるのでしょうか。「彼らは生きているだけで偉い,それに比べれば自分は恵まれた環境の中で何をしているのだろうか?」と思うことがグローバルヘルスの出発点だと思います。私たちは,学び考えることによって自分を有為な人材にし,持ち場ごとに自分の責務を果たしていくしかありません。そのために,熱帯医学・グローバルヘルス研究科を教員と学生が協力して教育,研究,実践を推進する意義のある場にしていきたいと考えています。

由井 克之 教授

    修了課程: 修了年度:

取得学位・資格

医学博士

個人/所属ウェブページ

http://www.med.nagasaki-u.ac.jp/mmi/im/

他所属

  • 大学院医歯薬学総合研究科
  • 感染免疫学講座
  • 免疫学分野

経歴

学歴

  • 1975-81    信州大学医学部
  • 1981-85    信州大学大学院医学研究科

職歴

  • 1985-1988    ペンシルバニア大学・病理部門・ポスドク
  • 1988             ペンシルバニア大学・病理部門・助手
  • 1989-1995    ペンシルバニア大学・病理部門・助教授
  • 1995-1997    長崎大学・医学部・医動物学・講師
  • 1997-2002    長崎大学・医学部・医動物学・教授
  • 2002-pres.     長崎大学・大学院医歯薬学総合研究科・教授

教育活動

感染免疫学

研究活動

マラリアは、世界中で毎年3~5億人の罹患者と100万人近くの死亡者があるきわめて重要な感染症です。しかしながら、有効なワクチンは開発されておら ず、決定的な対策が困難な感染症です。 マラリアは、原虫(単細胞の寄生虫)による感染症ですから、寄生体に関する研究と共に、宿主サイドの感染防御に関する研究を進めることが予防(ワクチン開 発)や治療法開発のために極めて重要です。また、マラリアに伴う様々な症状(発熱、貧血、肝脾腫など)や重症化(脳マラリアなど)には免疫系が深く関わっ ています。一方で、マラリア原虫感染は宿主の免疫機構を抑制しエスケープすることも知られています。しかしながら、これらのメカニズムは十分に理解されて いません。

  • (1)宿主の感染防御については、自然免疫、獲得免疫(B細胞とT細胞)が主要な研究対象になります。私達の教室では、T細胞を中心にマラリア感染に伴う 免疫系の修飾、免疫記憶に関する研究を行っています。最近の成果としては、マラリア感染に伴い、新たな免疫抑制細胞が誘導されることを発見しました。これ らは基礎的な研究ですが、近い将来には有効なマラリアワクチン開発につなげようという大きな夢をもっています。
  • (2)長崎大学の先輩であるの下村脩先生により発見された蛍光蛋白green fluorescent protein (GFP)の開発や、顕微鏡技術の革新により、生きた動物の感染現場を直接目で見ることが可能になりました。マラリア原虫感染における防御免疫の現場を直 接見る蛍光生体イメージングの研究に取り組んでいます。マラリア肝細胞期においてCD8+T細胞が肝細胞に感染したマラリア原虫を排除する現場を直接観察 することに成功しました。マラリア感染における免疫記憶細胞や制御性細胞の動態や活性化、寄生体・宿主相互作用など生体イメージングの手法を用いて解明し ていきます。

現在の主な研究活動地域

日本

最近の5つの出版物

  1. Kimura, D, Miyakoda, M., Kimura K., Honma, K., Hara, H., Yoshida, H., Yui, K.., Interleukin-27-producing CD4+ T cells regulate protective immunity during malaria parasite infection, Immunity, 44: 672-682, 2016.
  2. Akbari, M., Honma, K, Kimura, D., Miyakoda, M., Kimura,K, MatsuyamaT., Yui, K., IRF4 in dendritic cells inhibits IL-12 and controls Th1 immune responses against Leishmania major. J. Immunol., 192 (5): 2271-2279. 2014.
  3. Kimura, K., Kimura, D., Matsushima, Y., Miyakoda, M., Honma, K., Yuda, M., Yui, K., CD8+ T cells specific for a malaria cytoplasmic antigen form clusters around infected hepatocytes and are protective at the liver stage of infection, Inf. Immun. 81 (10) : 3825-3834. 2013.
  4. Closeup: Cross-presentation of malaria antigen by brain microvessels: why CD8+ T cells are critical for the pathogenesis of cerebral malaria.  EMBO Mol. Med. 5 (7):899-901、2013.
  5. Development of memory CD8+ T cells and their recall responses during blood-stage infection with    Plasmodium berghei ANKA. J. Immunol., 189(9):4396-4404. 2012.

メッセージ

免疫学を担当します。マラリア原虫感染を中心に感染免疫学,特にT細胞の機能制御と免疫記憶に関する基礎的な研究を行っています。熱帯感染症の多くは慢性感染症であり,ワクチンが開発されていません。慢性感染症は,そもそも自然感染で抵抗性を得にくい感染症ですので,ワクチン開発のためには越えなくてはならない壁がまだ多くあるのです。何が問題なのか,この対策をどのようにしたらよいか,皆さんと一緒に考えていきたいと思います。

稲岡 健 ダニエル 准教授

    修了課程: 修了年度:

取得学位・資格

薬学博士

ResearchGateアカウント

https://www.researchgate.net/profile/Daniel_Inaoka

他所属

東京大学医学系研究科・生物医化学教室・客員研究員

経歴

稲岡 健ダニエル博士(薬学)は2000年にブラジル東北部に位置するUniversidade Federal do Rio Grande do Norteで薬学部を卒業し、2000年から2005年の期間で東京大学薬学系研究科の修士及び博士課程を修了した。その後、東京大学医学系研究科で2007年までJSPS外国人特別研究員、2007年から2016年まで同研究科で助教として在籍した。長崎大学TMGHには2016年から助教(卓越)として赴任している。

教育活動

2002年から2005年まで、帝京大学医学部・物理学の非常勤講師として実習を担当。また、2007年から2016年まで東京大学医学系研究科・国際保健学専攻で生化学実習を担当した。長崎大学・TMGHではBasic Human Biologyの講義を北先生・神谷先生と共に講義を行う。

研究活動

稲岡は大学院でシャーガス病を引き起こすTrypanosoma cruziのピリミジン・エネルギー代謝経路の研究を行い、生化学・生物物理学・分子生物学・構造生物学・ケミカルバイオロジーといった手法を駆使して基礎研究及び創薬研究を行ってきた。外国人特別研究員・助教となってからは、分野を広げアフリカ睡眠病を引き起こすT. bruceiやリーシュマニア症を引き起こすLeishmania spp、熱帯熱マラリアを引き起こすPlasmodium falciparum等の寄生原虫の他、ブタ回虫(Ascaris suum)、アニサキス(Anisakis spp)、捻転胃虫(Haemonchus contortus)、肝蛭(Fasciola spp)、等の蠕虫で行われる微好気的エネルギー代謝の研究とそれによって支えられている寄生現象の分子機構を明らかにするための研究を行っている。その他にSATREPSプログラム「インドネシアの生物資源多様性を利用した抗マラリア・抗アメーバ新規薬剤リード化合物の探索」の研究分担者として、インドネシアで研究・実験の指導を行っている。対象疾患は幅広く、「寄生虫」、「ミトコンドリア」、「宿主環境適応」、「ユビキノン」、「エネルギー代謝」、「生化学」、「薬剤標的」、「薬剤開発」といったキーワードを基盤とした研究活動を行っている。

現在の主な研究活動地域

  • 日本
  • インドネシア
  • エル・サルバドル

最近の5つの出版物

  1. Hartuti ED, Inaoka DK (Corresponding Author, CA), Komatsuya K, Miyazaki Y, Miller RJ, Xinying W, Sadikin M, Prabandari EE, Waluyo D, Kuroda M, Amalia E, Matsuo Y, Nugroho NB, Saimoto H, Pramisandi A, Watanabe YI, Mori M, Shiomi K, Balogun EO, Shiba T, Harada S, Nozaki T, Kita K. Biochemical studies of membrane bound Plasmodium falciparum mitochondrial L-malate:quinone oxidoreductase, a potential drug target. Biochim Biophys Acta. 2018 Mar;1859(3):191-200.
  2. Wang X, Inaoka DK (CA), Shiba T, Balogun EO, Allmann S, Watanabe YI, Boshart M, Kita K, Harada S. Expression, purification, and crystallization of type 1 isocitrate dehydrogenase from Trypanosoma brucei brucei. Protein Expr Purif. 2017 Oct;138:56-62.
  3. Inaoka DK, Iida M, Hashimoto S, Tabuchi T, Kuranaga T, Balogun EO, Honma T, Tanaka A, Harada S, Nara T, Kita K, Inoue M. Design and synthesis of potent substrate-based inhibitors of the Trypanosoma cruzi dihydroorotate dehydrogenase. Bioorg Med Chem. 2017 Feb 15;25(4):1465-1470.
  4. Inaoka DK (CA), Iida M, Tabuchi T, Honma T, Lee N, Hashimoto S, Matsuoka S, Kuranaga T, Sato K, Shiba T, Sakamoto K, Balogun EO, Suzuki S, Nara T, Rocha JR, Montanari CA, Tanaka A, Inoue M, Kita K, Harada S. The Open Form Inducer Approach for Structure-Based Drug Design. PLoS One. 2016 Nov 28;11(11):e0167078.
  5. Inaoka DK, Shiba T, Sato D, Balogun EO, Sasaki T, Nagahama M, Oda M, Matsuoka S, Ohmori J, Honma T, Inoue M, Kita K, Harada S. Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria. Int J Mol Sci. 2015 Jul 7;16(7):15287-308.

井上 真吾 准教授

    修了課程: 修了年度:

取得学位・資格

獣医学博士、獣医師

個人/所属ウェブページ

http://www.tm.nagasaki-u.ac.jp/nekken/research/virology.html

他所属

熱帯医学研究所ウイルス学分野

経歴

  • 平成29年2月より熱研ウイルス学分野准教授として勤務(現在に至る)
  • 平成21年10月よりJICA専門家として約8年間ケニア中央医学研究所にてアルボウイルスの研究、国際協力事業(個別派遣、SATREPS等)を行う。
  • 平成13年12月より熱研ウイルス学分野助手(助教)として勤務
  • 平成11年4月から平成13年11月までフィリピン、セント・ルークスメディカルセンターにてポスドクとして研究(約3年間)
  • 平成9年4月から平成11年3月までポスドクとして熱研ウイルス学分野にて研究
  • 平成9年3月:岐阜大学大学院 連合獣医学研究科 獣医学専攻 博士課程修了
  • 平成3年7月まで:青年海外協力隊(獣医師隊員)としてザンビア共和国ザンビア大学獣医学部に勤務(3年間)
  • 昭和63年3月:北里大学大学院 獣医学研究科 獣医学専攻 修士課程修了

教育活動

  1. 熱帯医学研修課程および熱帯医学修士課程にてウイルス学実習を担当。
  2. ケニアにて博士課程3名(内2名は修了して学位取得)、修士課程4名(内2名は修了して学位取得)を指導。
  3. 日本にて博士課程進学予定のケニア人研究生2名とコンゴ民主共和国人1名の合計3名に対してウイルス学および分子生物学の基礎実験を指導中。

研究活動

蚊が媒介するウイルス(アルボウイルス)の迅速診断法の開発を主に行っている。(黄熱、デング熱、リフトバレー熱、チクングニア熱、日本脳炎、西ナイル熱など)

現在の主な研究活動地域

「ケニアにおける黄熱病およびリフトバレー熱に対する迅速診断法の開発とそのアウトブレイク警戒システムの構築プロジェクト」

本プロジェクトは、平成24年1月から平成29年1月までの5年間、地球規模課題対応国際科学技術協力(SATREPS)事業として実施された。ケニア中央医学研究所(Kenya Medical Research Institute:KEMRI)での黄熱病、リフトバレー熱の迅速診断法の実用化、リファレンス機能強化、更に、地域の医療施設、KEMRI、ケニア公衆衛生省を結ぶ携帯電話網を活用したアウトブレイク早期警戒・即時対応メカニズムの構築を目指している。本プロジェクト終了後の現在は、そのフォローアップ支援活動および共同学術研究を継続して行っている。

最近の5つの出版物

  1. Adungo F, Yu F, Kamau D, Inoue S, Hayasaka D, Posadas HG, Sang R, Mwau M, Morita K, Development and Characterization of monoclonal antibodies to yellow fever virus and their application in antigen detection and IgM capture ELISA. Clinical and Vaccine Immunology, on line 15 June 2016.1-38 (2016)
  2. Yoshikawa A, Nabeshima A, Inoue S, Agoh M, Morita K, Molecular and serological epidemiology of Japanese encephalitis virus (JEV) in a remote island of western Japan: an implication of JEV migration over the East China Sea., Tropical Medicine and Health, 44(8): 1-10 (2016)
  3. Inoue, S, Bundi M, Miring’u G, Muriithi B, Ashur S, Wandera E, Kathiiko C, Odoyo E, Kwallah AO, Galata A, Huka S, Shah M, Karama M, Kariuki S, Ichinose Y, Evaluation of a BSL-3 laboratory biosafety training program in Kenya. Journal of Biotechnology and Biosafety, 3(4): 288-296, (2015)
  4. Wasonga C, Inoue S, Rumberia, C,  Michuki, G, Kimotho JH, Ongus J, Sang R, Musila L, Genetic divergence of chikungunya virus plaque variants from the Comoros Island (2005). Virus Genes, 51(3): 323-328 (2015)
  5. Kwallah AO, Inoue S, Thairu-Mwangi AW, Kuttoh N, Morita K, Mwau M. Seroprevalence of Yellow Fever virus in selected health facilities in Western Kenya 2010–2012. Jpn J Infect Dis, 68: 230-234, (2015)

メッセージ

これまで主に蚊媒介性のウイルス(アルボウイルス)について留学生および派遣国での現地大学院生と共に研究活動を行ってきました。熱帯地域の現地のニーズに根差した研究および診断キットの開発を行うことを研究テーマ選びの最重要項目としています。

Vladimir Saenko 准教授

    修了課程: 修了年度:

取得学位・資格

More than a 30-year experience and hands-on a broad variety of molecular laboratory techniques and instrumentations, experimental design and data analysis, laboratory management, instructorship and supervision.

個人/所属ウェブページ

http://www-sdc.med.nagasaki-u.ac.jp/dhrc/index-e.html

ResearchGateアカウント

https://www.researchgate.net/profile/Vladimir_Saenko

他所属

Department of Radiation Molecular Epidemiology, Atomic Bomb Disease Institute, Nagasaki University

経歴

学歴
1995/011996/11, Postdoctoral Research Associate, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA1994/06, PhD (biochemistry and immunology), Rostov State Medical Institute, Rostov-on-Don, Russia1981/091987/02, M.S. [equivalent] in chemical engineering of biologically active substances, Lomonosov Institute of Fine Chemical Technology, Moscow, Russia

職歴

  • 2012/06present, Associate Professor, Department of Radiation Molecular Epidemiology
  • Atomic Bomb Disease Institute, Nagasaki University

  • 2011/042012/06, Assistant professor, Department of Health Risk Control, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences
  • 2002/042011/03, Assistant professor, Department of International Health and Radiation Research, Nagasaki University School of Medicine
  • 2000/05–2002/03, Visiting Professor, Department of International Health and Radiation Research, Nagasaki University School of Medicine
  • 1997/052000/04, Senior Scientist Molecular Biology division (Head), Department of Pathology, Medical Radiological research Center of RAMS, Obninsk, Russia
  • 1991/06–1997/04, Scientist, Department of Radiation Biochemistry, Medical Radiological research Center of RAMS, Obninsk, Russia
  • 1987/031991/05, Junior Scientist, Department of Radiation Biochemistry, Medical Radiological Research Center of RAMS, Obninsk, Russia

教育活動

  • 2013 – present, “Radiation and thyroid cancer” (medical student course), Fukushima Medical University
  • 2006 – 2014, “Molecular Biology, Gene expression, Genomics and Biotechnology” (foreign student course), Nagasaki University
  • 2003 – 2012, “Basics of Molecular Biology” (medical student course) Nagasaki University

研究活動

Thyroid carcinogenesis, molecular carcinogenesis, radiation-induced carcinogenesis, molecular epidemiology, molecular diagnostics, radiation and cancer epidemiology, radiation biology, human genetics, molecular pathology. An author and coauthor of 117 peer reviewed articles, 2 books, 9 book chapters, 23 Professional societies’ publications, peer review service to 19 international journals, Member of Editorial board in 2 journals.

現在の主な研究活動地域

日本

最近の5つの出版物

  1. Yamashita S, Suzuki S, Suzuki S, Shimura H, Saenko V. Lessons from Fukushima: Latest Findings of Thyroid Cancer after the Fukushima Nuclear Power Plant Accident. Thyroid 2017 Dec 1. doi: 10.1089/thy.2017.0283. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/28954584
  2. Bogdanova TI, Saenko V, Hirokawa M, Ito M, Zurnadzhy LY, Hayashi T, Rogounovitch TI, Miyauchi A, Tronko MD, Yamashita S. Comparative histopathological analysis of sporadic pediatric papillary thyroid carcinoma from Japan and Ukraine. Endocr J 2017, 64(10):977-993. doi: 10.1507/endocrj.EJ17-0134. https://www.jstage.jst.go.jp/article/endocrj/64/10/64_EJ17-0134/_pdf/-char/en
  3. Matsuse M, Yabuta T, Saenko V, Hirokawa M, Nishihara E, Suzuki K, Yamashita S, Miyauchi A, Mitsutake N. TERT promoter mutations and Ki-67 labeling index as a prognostic marker of papillary thyroid carcinomas: combination of two independent factors. Scientific Rep 2017, 7:41752 doi: 10.1038/srep41752. PMID: 28150740. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288691/
  4. Nikitski A, Rogounovitch T, Bychkov A, Takahashi M, Yoshiura K, Mitsutake N, Kawaguchi T, Matsuse M, Drozd V, Demidchik Yu, Nishihara E, Hirokawa M, Miyauchi A, Rubanovich A, Matsuda F, Yamashita S, Saenko V. Genotype analyses in the Japanese and Belarusian populations reveal independent effects of rs965513 and rs1867277 but do not support the role of FOXE1 polyalanine tract length in conferring risk for papillary thyroid carcinoma. Thyroid 2017, 27(2):224-235. doi: 10.1089/thy.2015.0541. http://online.liebertpub.com/doi/pdf/10.1089/thy.2015.0541
  5. Takamura N, Orita M, Saenko V, Yamashita S, Nagataki S, Demidchik Yu. Radiation and risk of thyroid cancer: Fukushima and Chernobyl. Lancet Diabetes Endocrinol 2016, 4(8):647. http://www.sciencedirect.com/science/article/pii/S2213858716301127?via%3Dihub

メッセージ

We are aimed at designing and conducting laboratory and epidemiological research into the contribution of inherited genetic variations and somatic genetic alterations to the etiology of human cancer and non-cancer diseases, particularly focusing on populations exposed to radiation in Chernobyl, Kazakhstan and Japan to improve public health through gaining new insights into gene-environmental interactions.

Chris Fook Sheng Ng 准教授

    修了課程: 修了年度:

取得学位・資格

BSc, MAppStats, PhD

Research gate/Linked-in アカウント

Researchmap: https://researchmap.jp/chrisng
ORCID: https://orcid.org/0000-0003-1025-0807
Leave Chris a message at https://tinyurl.com/yc3chlms

所属

School of Tropical Medicine and Global Health, Nagasaki University, Japan

経歴

Chris received his Bachelor of Science from the University of Nebraska-Lincoln (USA) (2002), a Master of Applied Statistics with distinction from the University of Malaya (Malaysia) (2005), and a PhD in Health Science from the University of Tokyo (Japan) (2011) for research on statistical method to measure the relative performance of post-market treatments in the absence of suitable controls. Following completion of his PhD, he went on to hold a postdoctoral position at the National Institute for Environmental Studies (Japan) where he studied the health effects of ambient temperatures and air pollution in Japan. In 2013, he became a postdoctoral fellow under the Japan Society for the Promotion of Science and expanded his work on environmental pollution and health to the developing countries in the tropics. He continued his work as an assistant professor at the Institute of Tropical Medicine, Nagasaki University (Japan), from late 2015 until early 2018. In April 2018, he joined the School of Tropical Medicine and Global Health at the same university as an Associate Professor. He was a Rutherford Fellow at the London School of Hygiene and Tropical Medicine (United Kingdom) between August 2018 to January 2019.

教育活動

Chris teaches biostatistics and environmental epidemiology at the School of Tropical Medicine and Global Health at Nagasaki University, and previously, the School of International Health at the University of Tokyo. He has previously organized and taught undergraduate courses in statistics, actuarial mathematics, and quantitative analysis.

研究活動

Chris is interested in environmental epidemiology and the related statistical methods. His research focuses on the assessment of human health risk associated with atmospheric exposures such as air pollution, ambient temperatures, airborne pollen, and intercontinental dust events. He is currently leading a multi-city study to quantify the mortality risk of desert dust pollution identified using a hybrid of ground- and space-borne measurements. He is also leading a project to measure the health impacts of landscape fires that affect the air quality of many Southeast Asian cities. Recently, he has completed a project that investigates the associations of fine particulate matter, its chemical constituents and sources with the lung function of severe asthma patients exposed to a low level of air pollution.

Given his extensive training in applied statistics, Chris is also interested in the application of statistics in a multidisciplinary context involving other health fields and looks forward to working with researchers from different backgrounds.

現在の主な研究活動地域

Studies and collaborations in Japan, Malaysia, Philippines, Vietnam, Thailand, Indonesia and China.

最近の5つの出版物

  1. Ng CFS, Hashizume M, Obase Y, Doi M, Tamura K, Tomari S, Kawano T, Fukushima C, Matsuse H, Chung Y, Kim Y, Kunimitsu K, Kohno S, Mukae H. Associations of chemical composition and sources of PM2.5 with lung function of severe asthmatic adults in a low air pollution environment of urban Nagasaki, Japan. Environmental Pollution. 2019; 252: 599-606. https://doi.org/10.1016/j.envpol.2019.05.117
  2. Ng CFS, Boeckmann M, Ueda K, Zeeb H, Nitta H, Watanabe C, Honda Y. Heat-related mortality: effect modification and adaptation in Japan from 1972 to 2010. Global Environmental Change. 2016; 39: 234-243. https://doi.org/10.1016/j.gloenvcha.2016.05.006
  3. Ng CFS, Stickley A, Konishi S, Watanabe C. Ambient air pollution and suicide in Tokyo, 2001-2011. Journal of Affective Disorders. 2016; 201: 194-202. https://doi.org/10.1016/j.jad.2016.05.006
  4. Ng CFS, Ueda K, Takeuchi A, Nitta H, Konishi S, Bagrowicz R, Watanabe C, Takami A. Socio-geographic variation in the effects of heat and cold on daily mortality in Japan. Journal of Epidemiology. 2014; 24(1): 15-24. https://doi.org/10.2188/jea.JE20130051
  5. Ng CFS, Ueda K, Ono M, Nitta H, Takami A. Characterizing the effect of summer temperature on heat-stroke-related emergency ambulance dispatches in the Kanto area of Japan. International Journal of Biometeorology. 2014; 58(5): 941-948. https://doi.org/10.1007/s00484-013-0677-4

メッセージ

In a digital age where data are collected faster and greater in quantity, strong quantitative skills are important to extract useful information for meaningful interpretations to inform policies. Statistics is central to this process. As you begin your journey with us, there will be opportunities to gain knowledge in statistical inference and develop skills in data analysis. You will learn to appreciate the data-driven approach in epidemiology. I look forward to meeting students and researchers interested in utilizing these skills to improve health.

樋泉 道子 准教授

    修了課程: 修了年度:

取得学位・資格

  • MD
  • MTM
  • PhD

個人/所属ウェブページ

http://www.tm.nagasaki-u.ac.jp/pediatric/

他所属

Department of Pediatric Infectious Diseases, Institute of Tropical Medicine (NEKKEN), Nagasaki University

経歴

I graduated from Kumamoto University Medical School, Japan and then had worked as a pediatrician for 8 years. Following that, I had studied tropical medicine and pediatric infectious diseases in the Master course of Tropical Medicine and in the Doctoral course in Graduate School of Biomedical Sciences, Nagasaki University. After I received my PhD, I joined the Department of Pediatric Infectious Diseases, the Institute of Tropical Medicine, Nagasaki University as an assistant professor in 2015.

教育活動

Facilitator of Epidemiology-Statistics Course in School of Tropical Medicine and Global Health, Nagasaki University

研究活動

Studies on pediatric infectious diseases in Vietnam:
Acute respiratory infections (incidence, viral/bacterial pathogens, risk factors)
Congenital infections (e.g.,rubella, CMV, Zika) and the effect on child development
Pneumococcal conjugate vaccine reduced dosing trial

現在の主な研究活動地域

ベトナム

最近の5つの出版物

  1. Michiko Toizumi, Motoi Suzuki, Hien Anh Thi Nguyen, Minh Nhat Le, Koya Ariyoshi, Hiroyuki Moriuchi, Masahiro Hashizume, Duc Anh Dang, and Lay-Myint Yoshida
    Viral Acute Respiratory Illnesses in Young Infants Increase the Risk of Respiratory Readmission
    The Pediatric Infectious Disease Journal, in press
  2. Imai, C., Toizumi, M., Hall, L., Lambert, S., Halton, K., Merollini, K.
    A systematic review and meta-analysis of the direct epidemiological and economic effects of seasonal influenza vaccination on healthcare workers
    (2018) PLoS ONE, 13 (6), art. no. e0198685
  3. Toizumi, M., Nguyen, G.T.H., Motomura, H., Nguyen, T.H., Pham, E., Kaneko, K.-I., Uematsu, M., Nguyen, H.A.T., Dang, D.A., Hashizume, M., Yoshida, L.-M., Moriuchi, H.
    Sensory defects and developmental delay among children with congenital rubella syndrome
    (2017) Scientific Reports, 7, art. no. 46483.
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017447271&doi=10.1038%2fsrep46483&partnerID=40&md5=e4958d50959615e2658576c987ed1bc9
    DOI: 10.1038/srep46483
  4. Yoshihara, K., Le, M.N., Okamoto, M., Wadagni, A.C.A., Nguyen, H.A., Toizumi, M., Pham, E., Suzuki, M., Nguyen, A.T.T., Oshitani, H., Ariyoshi, K., Moriuchi, H., Hashizume, M., Dang, D.A., Yoshida, L.-M.
    Association of RSV-A ON1 genotype with Increased Pediatric Acute Lower Respiratory Tract Infection in Vietnam
    (2016) Scientific Reports, 6, art. no. 27856.
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-84975155668&doi=10.1038%2fsrep27856&partnerID=40&md5=762505b0e9f3febd2b4412a119cb6ba8
    DOI: 10.1038/srep27856
  5. Yamanashi, H., Ngoc, M.Q., Van Huy, T., Suzuki, M., Tsujino, A., Toizumi, M., Takahashi, K., Thiem, V.D., Anh, D.D., Anh, N.T.H., Tho, L.H., Maeda, T., Cox, S.E., Yoshida, L.-M., Ariyoshi, K.
    Population-based incidence rates of first-ever stroke in central Vietnam
    (2016) PLoS ONE, 11 (8), art. no. e0160665.
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983475347&doi=10.1371%2fjournal.pone.0160665&partnerID=40&md5=ffb48a6308a404bd39460f8ddd42f7ab
    DOI: 10.1371/journal.pone.0160665

メッセージ

Please join us if you are interested in our researches on pediatric infectious diseases!

さらに記事を表示する
PAGE TOP