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稲岡 健 ダニエル 准教授

    修了課程: 修了年度:

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薬学博士

ResearchGateアカウント

https://www.researchgate.net/profile/Daniel_Inaoka

他所属

東京大学医学系研究科・生物医化学教室・客員研究員

経歴

稲岡 健ダニエル博士(薬学)は2000年にブラジル東北部に位置するUniversidade Federal do Rio Grande do Norteで薬学部を卒業し、2000年から2005年の期間で東京大学薬学系研究科の修士及び博士課程を修了した。その後、東京大学医学系研究科で2007年までJSPS外国人特別研究員、2007年から2016年まで同研究科で助教として在籍した。長崎大学TMGHには2016年から助教(卓越)として赴任している。

教育活動

2002年から2005年まで、帝京大学医学部・物理学の非常勤講師として実習を担当。また、2007年から2016年まで東京大学医学系研究科・国際保健学専攻で生化学実習を担当した。長崎大学・TMGHではBasic Human Biologyの講義を北先生・神谷先生と共に講義を行う。

研究活動

稲岡は大学院でシャーガス病を引き起こすTrypanosoma cruziのピリミジン・エネルギー代謝経路の研究を行い、生化学・生物物理学・分子生物学・構造生物学・ケミカルバイオロジーといった手法を駆使して基礎研究及び創薬研究を行ってきた。外国人特別研究員・助教となってからは、分野を広げアフリカ睡眠病を引き起こすT. bruceiやリーシュマニア症を引き起こすLeishmania spp、熱帯熱マラリアを引き起こすPlasmodium falciparum等の寄生原虫の他、ブタ回虫(Ascaris suum)、アニサキス(Anisakis spp)、捻転胃虫(Haemonchus contortus)、肝蛭(Fasciola spp)、等の蠕虫で行われる微好気的エネルギー代謝の研究とそれによって支えられている寄生現象の分子機構を明らかにするための研究を行っている。その他にSATREPSプログラム「インドネシアの生物資源多様性を利用した抗マラリア・抗アメーバ新規薬剤リード化合物の探索」の研究分担者として、インドネシアで研究・実験の指導を行っている。対象疾患は幅広く、「寄生虫」、「ミトコンドリア」、「宿主環境適応」、「ユビキノン」、「エネルギー代謝」、「生化学」、「薬剤標的」、「薬剤開発」といったキーワードを基盤とした研究活動を行っている。

現在の主な研究活動地域

  • 日本
  • インドネシア
  • エル・サルバドル

最近の5つの出版物

  1. Hartuti ED, Inaoka DK (Corresponding Author, CA), Komatsuya K, Miyazaki Y, Miller RJ, Xinying W, Sadikin M, Prabandari EE, Waluyo D, Kuroda M, Amalia E, Matsuo Y, Nugroho NB, Saimoto H, Pramisandi A, Watanabe YI, Mori M, Shiomi K, Balogun EO, Shiba T, Harada S, Nozaki T, Kita K. Biochemical studies of membrane bound Plasmodium falciparum mitochondrial L-malate:quinone oxidoreductase, a potential drug target. Biochim Biophys Acta. 2018 Mar;1859(3):191-200.
  2. Wang X, Inaoka DK (CA), Shiba T, Balogun EO, Allmann S, Watanabe YI, Boshart M, Kita K, Harada S. Expression, purification, and crystallization of type 1 isocitrate dehydrogenase from Trypanosoma brucei brucei. Protein Expr Purif. 2017 Oct;138:56-62.
  3. Inaoka DK, Iida M, Hashimoto S, Tabuchi T, Kuranaga T, Balogun EO, Honma T, Tanaka A, Harada S, Nara T, Kita K, Inoue M. Design and synthesis of potent substrate-based inhibitors of the Trypanosoma cruzi dihydroorotate dehydrogenase. Bioorg Med Chem. 2017 Feb 15;25(4):1465-1470.
  4. Inaoka DK (CA), Iida M, Tabuchi T, Honma T, Lee N, Hashimoto S, Matsuoka S, Kuranaga T, Sato K, Shiba T, Sakamoto K, Balogun EO, Suzuki S, Nara T, Rocha JR, Montanari CA, Tanaka A, Inoue M, Kita K, Harada S. The Open Form Inducer Approach for Structure-Based Drug Design. PLoS One. 2016 Nov 28;11(11):e0167078.
  5. Inaoka DK, Shiba T, Sato D, Balogun EO, Sasaki T, Nagahama M, Oda M, Matsuoka S, Ohmori J, Honma T, Inoue M, Kita K, Harada S. Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria. Int J Mol Sci. 2015 Jul 7;16(7):15287-308.

Vladimir Saenko 准教授

    修了課程: 修了年度:

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More than a 30-year experience and hands-on a broad variety of molecular laboratory techniques and instrumentations, experimental design and data analysis, laboratory management, instructorship and supervision.

個人/所属ウェブページ

http://www-sdc.med.nagasaki-u.ac.jp/dhrc/index-e.html

ResearchGateアカウント

https://www.researchgate.net/profile/Vladimir_Saenko

他所属

Department of Radiation Molecular Epidemiology, Atomic Bomb Disease Institute, Nagasaki University

経歴

学歴
1995/011996/11, Postdoctoral Research Associate, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA1994/06, PhD (biochemistry and immunology), Rostov State Medical Institute, Rostov-on-Don, Russia1981/091987/02, M.S. [equivalent] in chemical engineering of biologically active substances, Lomonosov Institute of Fine Chemical Technology, Moscow, Russia

職歴

  • 2012/06present, Associate Professor, Department of Radiation Molecular Epidemiology Atomic Bomb Disease Institute, Nagasaki University
  • 2011/042012/06, Assistant professor, Department of Health Risk Control, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences
  • 2002/042011/03, Assistant professor, Department of International Health and Radiation Research, Nagasaki University School of Medicine
  • 2000/05–2002/03, Visiting Professor, Department of International Health and Radiation Research, Nagasaki University School of Medicine
  • 1997/052000/04, Senior Scientist Molecular Biology division (Head), Department of Pathology, Medical Radiological research Center of RAMS, Obninsk, Russia
  • 1991/06–1997/04, Scientist, Department of Radiation Biochemistry, Medical Radiological research Center of RAMS, Obninsk, Russia
  • 1987/031991/05, Junior Scientist, Department of Radiation Biochemistry, Medical Radiological Research Center of RAMS, Obninsk, Russia

 

教育活動

  • 2013 – present, “Radiation and thyroid cancer” (medical student course), Fukushima Medical University
  • 2006 – 2014, “Molecular Biology, Gene expression, Genomics and Biotechnology” (foreign student course), Nagasaki University
  • 2003 – 2012, “Basics of Molecular Biology” (medical student course) Nagasaki University

研究活動

Thyroid carcinogenesis, molecular carcinogenesis, radiation-induced carcinogenesis, molecular epidemiology, molecular diagnostics, radiation and cancer epidemiology, radiation biology, human genetics, molecular pathology. An author and coauthor of 117 peer reviewed articles, 2 books, 9 book chapters, 23 Professional societies’ publications, peer review service to 19 international journals, Member of Editorial board in 2 journals.

現在の主な研究活動地域

日本

最近の5つの出版物

  1. Yamashita S, Suzuki S, Suzuki S, Shimura H, Saenko V. Lessons from Fukushima: Latest Findings of Thyroid Cancer after the Fukushima Nuclear Power Plant Accident. Thyroid 2017 Dec 1. doi: 10.1089/thy.2017.0283. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/28954584
  2. Bogdanova TI, Saenko V, Hirokawa M, Ito M, Zurnadzhy LY, Hayashi T, Rogounovitch TI, Miyauchi A, Tronko MD, Yamashita S. Comparative histopathological analysis of sporadic pediatric papillary thyroid carcinoma from Japan and Ukraine. Endocr J 2017, 64(10):977-993. doi: 10.1507/endocrj.EJ17-0134. https://www.jstage.jst.go.jp/article/endocrj/64/10/64_EJ17-0134/_pdf/-char/en
  3. Matsuse M, Yabuta T, Saenko V, Hirokawa M, Nishihara E, Suzuki K, Yamashita S, Miyauchi A, Mitsutake N. TERT promoter mutations and Ki-67 labeling index as a prognostic marker of papillary thyroid carcinomas: combination of two independent factors. Scientific Rep 2017, 7:41752 doi: 10.1038/srep41752. PMID: 28150740. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288691/
  4. Nikitski A, Rogounovitch T, Bychkov A, Takahashi M, Yoshiura K, Mitsutake N, Kawaguchi T, Matsuse M, Drozd V, Demidchik Yu, Nishihara E, Hirokawa M, Miyauchi A, Rubanovich A, Matsuda F, Yamashita S, Saenko V. Genotype analyses in the Japanese and Belarusian populations reveal independent effects of rs965513 and rs1867277 but do not support the role of FOXE1 polyalanine tract length in conferring risk for papillary thyroid carcinoma. Thyroid 2017, 27(2):224-235. doi: 10.1089/thy.2015.0541. http://online.liebertpub.com/doi/pdf/10.1089/thy.2015.0541
  5. Takamura N, Orita M, Saenko V, Yamashita S, Nagataki S, Demidchik Yu. Radiation and risk of thyroid cancer: Fukushima and Chernobyl. Lancet Diabetes Endocrinol 2016, 4(8):647. http://www.sciencedirect.com/science/article/pii/S2213858716301127?via%3Dihub

メッセージ

We are aimed at designing and conducting laboratory and epidemiological research into the contribution of inherited genetic variations and somatic genetic alterations to the etiology of human cancer and non-cancer diseases, particularly focusing on populations exposed to radiation in Chernobyl, Kazakhstan and Japan to improve public health through gaining new insights into gene-environmental interactions.

Chris Fook Sheng Ng 准教授

    修了課程: 修了年度:

取得学位・資格

BSc, MAppStats, PhD

Research gate/Linked-in アカウント

Researchmap: https://researchmap.jp/chrisng
ORCID: https://orcid.org/0000-0003-1025-0807
Leave Chris a message at https://tinyurl.com/yc3chlms

所属

School of Tropical Medicine and Global Health, Nagasaki University, Japan

経歴

Chris received his Bachelor of Science from the University of Nebraska-Lincoln (USA) (2002), a Master of Applied Statistics with distinction from the University of Malaya (Malaysia) (2005), and a PhD in Health Science from the University of Tokyo (Japan) (2011) for research on statistical method to measure the relative performance of post-market treatments in the absence of suitable controls. Following completion of his PhD, he went on to hold a postdoctoral position at the National Institute for Environmental Studies (Japan) where he studied the health effects of ambient temperatures and air pollution in Japan. In 2013, he became a postdoctoral fellow under the Japan Society for the Promotion of Science and expanded his work on environmental pollution and health to the developing countries in the tropics. He continued his work as an assistant professor at the Institute of Tropical Medicine, Nagasaki University (Japan), from late 2015 until early 2018. In April 2018, he joined the School of Tropical Medicine and Global Health at the same university as an Associate Professor. He was a Rutherford Fellow at the London School of Hygiene and Tropical Medicine (United Kingdom) between August 2018 to January 2019.

教育活動

Chris teaches biostatistics and environmental epidemiology at the School of Tropical Medicine and Global Health at Nagasaki University, and previously, the School of International Health at the University of Tokyo. He has previously organized and taught undergraduate courses in statistics, actuarial mathematics, and quantitative analysis.

研究活動

Chris is interested in environmental epidemiology and the related statistical methods. His research focuses on the assessment of human health risk associated with atmospheric exposures such as air pollution, ambient temperatures, airborne pollen, and intercontinental dust events. He is currently leading a multi-city study to quantify the mortality risk of desert dust pollution identified using a hybrid of ground- and space-borne measurements. He is also leading a project to measure the health impacts of landscape fires that affect the air quality of many Southeast Asian cities. Recently, he has completed a project that investigates the associations of fine particulate matter, its chemical constituents and sources with the lung function of severe asthma patients exposed to a low level of air pollution.

Given his extensive training in applied statistics, Chris is also interested in the application of statistics in a multidisciplinary context involving other health fields and looks forward to working with researchers from different backgrounds.

現在の主な研究活動地域

Studies and collaborations in Japan, Malaysia, Philippines, Vietnam, Thailand, Indonesia and China.

最近の5つの出版物

  1. Ng CFS, Hashizume M, Obase Y, Doi M, Tamura K, Tomari S, Kawano T, Fukushima C, Matsuse H, Chung Y, Kim Y, Kunimitsu K, Kohno S, Mukae H. Associations of chemical composition and sources of PM2.5 with lung function of severe asthmatic adults in a low air pollution environment of urban Nagasaki, Japan. Environmental Pollution. 2019; 252: 599-606. https://doi.org/10.1016/j.envpol.2019.05.117
  2. Ng CFS, Boeckmann M, Ueda K, Zeeb H, Nitta H, Watanabe C, Honda Y. Heat-related mortality: effect modification and adaptation in Japan from 1972 to 2010. Global Environmental Change. 2016; 39: 234-243. https://doi.org/10.1016/j.gloenvcha.2016.05.006
  3. Ng CFS, Stickley A, Konishi S, Watanabe C. Ambient air pollution and suicide in Tokyo, 2001-2011. Journal of Affective Disorders. 2016; 201: 194-202. https://doi.org/10.1016/j.jad.2016.05.006
  4. Ng CFS, Ueda K, Takeuchi A, Nitta H, Konishi S, Bagrowicz R, Watanabe C, Takami A. Socio-geographic variation in the effects of heat and cold on daily mortality in Japan. Journal of Epidemiology. 2014; 24(1): 15-24. https://doi.org/10.2188/jea.JE20130051
  5. Ng CFS, Ueda K, Ono M, Nitta H, Takami A. Characterizing the effect of summer temperature on heat-stroke-related emergency ambulance dispatches in the Kanto area of Japan. International Journal of Biometeorology. 2014; 58(5): 941-948. https://doi.org/10.1007/s00484-013-0677-4

メッセージ

In a digital age where data are collected faster and greater in quantity, strong quantitative skills are important to extract useful information for meaningful interpretations to inform policies. Statistics is central to this process. As you begin your journey with us, there will be opportunities to gain knowledge in statistical inference and develop skills in data analysis. You will learn to appreciate the data-driven approach in epidemiology. I look forward to meeting students and researchers interested in utilizing these skills to improve health.

樋泉 道子 准教授

    修了課程: 修了年度:

取得学位・資格

  • MD
  • MTM
  • PhD

個人/所属ウェブページ

http://www.tm.nagasaki-u.ac.jp/pediatric/

他所属

Department of Pediatric Infectious Diseases, Institute of Tropical Medicine (NEKKEN), Nagasaki University

経歴

I graduated from Kumamoto University Medical School, Japan and then had worked as a pediatrician for 8 years. Following that, I had studied tropical medicine and pediatric infectious diseases in the Master course of Tropical Medicine and in the Doctoral course in Graduate School of Biomedical Sciences, Nagasaki University. After I received my PhD, I joined the Department of Pediatric Infectious Diseases, the Institute of Tropical Medicine, Nagasaki University as an assistant professor in 2015.

教育活動

Facilitator of Epidemiology-Statistics Course in School of Tropical Medicine and Global Health, Nagasaki University

研究活動

Studies on pediatric infectious diseases in Vietnam:
Acute respiratory infections (incidence, viral/bacterial pathogens, risk factors)
Congenital infections (e.g.,rubella, CMV, Zika) and the effect on child development
Pneumococcal conjugate vaccine reduced dosing trial

現在の主な研究活動地域

ベトナム

最近の5つの出版物

  1. Michiko Toizumi, Motoi Suzuki, Hien Anh Thi Nguyen, Minh Nhat Le, Koya Ariyoshi, Hiroyuki Moriuchi, Masahiro Hashizume, Duc Anh Dang, and Lay-Myint Yoshida
    Viral Acute Respiratory Illnesses in Young Infants Increase the Risk of Respiratory Readmission
    The Pediatric Infectious Disease Journal, in press
  2. Imai, C., Toizumi, M., Hall, L., Lambert, S., Halton, K., Merollini, K.
    A systematic review and meta-analysis of the direct epidemiological and economic effects of seasonal influenza vaccination on healthcare workers
    (2018) PLoS ONE, 13 (6), art. no. e0198685
  3. Toizumi, M., Nguyen, G.T.H., Motomura, H., Nguyen, T.H., Pham, E., Kaneko, K.-I., Uematsu, M., Nguyen, H.A.T., Dang, D.A., Hashizume, M., Yoshida, L.-M., Moriuchi, H.
    Sensory defects and developmental delay among children with congenital rubella syndrome
    (2017) Scientific Reports, 7, art. no. 46483.
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017447271&doi=10.1038%2fsrep46483&partnerID=40&md5=e4958d50959615e2658576c987ed1bc9
    DOI: 10.1038/srep46483
  4. Yoshihara, K., Le, M.N., Okamoto, M., Wadagni, A.C.A., Nguyen, H.A., Toizumi, M., Pham, E., Suzuki, M., Nguyen, A.T.T., Oshitani, H., Ariyoshi, K., Moriuchi, H., Hashizume, M., Dang, D.A., Yoshida, L.-M.
    Association of RSV-A ON1 genotype with Increased Pediatric Acute Lower Respiratory Tract Infection in Vietnam
    (2016) Scientific Reports, 6, art. no. 27856.
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-84975155668&doi=10.1038%2fsrep27856&partnerID=40&md5=762505b0e9f3febd2b4412a119cb6ba8
    DOI: 10.1038/srep27856
  5. Yamanashi, H., Ngoc, M.Q., Van Huy, T., Suzuki, M., Tsujino, A., Toizumi, M., Takahashi, K., Thiem, V.D., Anh, D.D., Anh, N.T.H., Tho, L.H., Maeda, T., Cox, S.E., Yoshida, L.-M., Ariyoshi, K.
    Population-based incidence rates of first-ever stroke in central Vietnam
    (2016) PLoS ONE, 11 (8), art. no. e0160665.
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983475347&doi=10.1371%2fjournal.pone.0160665&partnerID=40&md5=ffb48a6308a404bd39460f8ddd42f7ab
    DOI: 10.1371/journal.pone.0160665

メッセージ

Please join us if you are interested in our researches on pediatric infectious diseases!

Nguyen Tien Huy 准教授

    修了課程: 修了年度:

取得学位・資格

MD, PhD

個人/所属ウェブページ

http://www.onlineresearchclub.org/
https://www.facebook.com/onlineresearchclub

Facebook

https://www.facebook.com/nguyentien.huy.319/

ResearchGate/LinkedInアカウント

https://www.researchgate.net/profile/Huy_Nguyen2

Publications in Scopus

https://www.scopus.com/authid/detail.uri?origin=resultslist&authorId=7003362869&zone=

他所属

School of Tropical Medicine and Global Health, Nagasaki University
Department of Immunogenetics, Institute of Tropical Medicine (NEKKEN), Nagasaki University

経歴

I earned my M.D. as the valedictorian at Ho Chi Minh University of Medicine and Pharmacy, Ho Chi Minh City (Vietnam) in 1996. Then I worked as an intern clinical medical doctor at Infectious Diseases Department of Ho Chi Minh University of Medicine and Pharmacy and also worked at the Hospital of Tropical Diseases in Ho Chi Minh City until 1998. In 2002, I gained my PhD at Kyoto Institute of Technology (Kyoto, Japan) with a thesis on the antimalarial mechanism. Between 2002 and 2007, I worked a postdoctoral fellow at Kyoto Institute of Technology. From 2007, I have been working and teaching for Nagasaki University on a broad field of research including clinical research, epidemiology, global health, ethical issues, education, research methodology, evidence based, and health policy using various skill sets of biostatistics, data mining, survey, and systematic review and meta-analysis.

教育活動

  1. TMGH

-Systematic Review and Meta-analysis: Interpretation and Conduction
-Key skill of “how to write a literature review of dissertation and efficient search”.

  1. Online teaching

-All steps of conducting clinical research, systematic review/meta-analysis, and health survey (https://www.facebook.com/groups/1060208227483290)

研究活動

  • Systematic review and meta-analysis
  • Survey on global health and medicine
  • Methodological research
  • Analysis of registry data
  • Clinical research
  • Health policies and countries’ measures against COVID-19

現在の主な研究活動地域

Global

最近の5つの出版物

  1. Ibrahim Y, Raut A, Varney J, Sidhu A, Dong V, Huy NT (Corresponding author: CA). Lessons Learned from the Re-emergent COVID-19 Cases in Areas of Long Reported No Community Transmission. Clin Infect Dis. 2020 Sep 24:ciaa1438. doi: 10.1093/cid/ciaa1438
  2. Shah J, Karimzadeh S, Al-Ahdal TMA, Mousavi SH, Zahid SU, Huy NT. COVID-19: the current situation in Afghanistan. Lancet Glob Health. 2020 Jun;8(6):e771-e772.
  3. Tran L, Y MN, Thai Le Ba Nghia TLB, Hendam A, Vuong NL, Alzalal E, Ahmed M. Sayed AM, Hussain MM, Akash Sharma A, Tieu T, Peterson Gitonga Mathenge PG, Hirayama K, Alexander N, Huy NT (CA). Frequent inappropriate use of unweighted summary statistics in systematic reviews of pathogen genotypes or genogroups. J Clin Epidemiol. 2020 Mar;119:26-35. doi: 10.1016
  4. Ahmed AM, Giang HTN, Sherief G, Hosni S, Altibi AM, Huynh S, Tang NA, Cuong T, Tuan LQA, Vuong NL, Mohamed A, Ghorab, Muhammad, Ngan T, Sameh E, Elmaraezy A, Minh LHN, Hirayama K, Huy NT (CA). Introduction of novel surgical techniques: A survey on knowledge, attitude, and practice of surgeons. Surgical Innovation. 2019 Oct; 26(5):560-572.
  5. Tam NT, Huy NT (CA) Thoa LTB, Long NP, Trang NTH, Hirayama K, and Karbwang J. (2015, Mar); Three decades of participants’ understanding of informed consent in clinical trials: a systematic review and meta-analysis. Bulletin of the World Health Organization. 2015 Mar; 93(3):186-198H

メッセージ

 My “teaching slogan” is “anyone can do research and publish the paper under the proper supervision”. Therefore, my teaching mainly focuses on conducting real research and learn from failure and success of each research. Because I have experience in various fields of medicine and health, I am able to help students in further discussion of developing their ideas, should they have difficulty finding a supervisor in those particular fields.
 I established the Online Research Club for medical students in 2010 to enhance global medical students’ research success, using an online education program. On the occasional of joining TMGH this year, I opened an Online Research Education Program (ORCEP) for TMGH students and alumni to continuously learn with global students and help one another. The Online Research Education Program (ORCEP) provides an online Facebook-based mentoring platform and research environment for students to explore the world of research under the supervision of established researchers. The ORCEP serves to equip students with basic research knowledge and practical skills in conducting research, which includes idea development, protocol preparation, data collection and management, advanced scientific writing, data analysis, collaboration, and leadership. Health and medical students, as well as young health care workers without any research experiences, along with research supervisors in the field of medicine and global health, are all welcome to join the program by sending email to tienhuy@nagasaki-u.ac.jp or requesting to join the group at https://www.facebook.com/groups/1060208227483290/.  An active new student can expect to gain the experience to conduct research and get at least one publication after two years.
 All TMGH students and alumni are welcome to join. Non-TMGH students, however, must 1) have a valid ID card, a transparent and active Facebook; 2) have not joined or conducted any research yet; 3) have not involved in any research group yet; and 4) spend at least 30 min per day to learn and conduct the research.

Bhim Gopal Dhoubhadel 准教授

    修了課程: 修了年度:

取得学位・資格

MBBS, MTM, PhD

ResearchGate/LinkedInアカウント

Twitterアカウント

https://twitter.com/bhim_gopal

経歴

I received my medical degree from BP Koirala Institute of Health Sciences (BPKIHS), Nepal in 2005 and then worked for three years in paediatric hospitals in Nepal followed by one year in a refugee camp for Somali and Ethiopian refugees under UNHCR in Djibouti. Between 2010-11, I completed the Master of Tropical Medicine (MTM) programme in the Institute of Tropical Medicine, Nagasaki University and then a PhD in the Department of Clinical Medicine of the same institute between 2011 and 2014. In 2014, I was a Fellow of the Global (Health) Leadership Program at the University of Tokyo and completed an internship at the headquarters of the World Health Organization (WHO) in Geneva. My research interests are infectious diseases, child health and development of new diagnostic assays. In 2014, we established a new diagnostic assay for serotyping the pneumococcus (a major cause of pneumonia). The assay can identify vaccine serotypes easily and conveniently at a relatively low cost and has been applied in studies in Japan, Vietnam and Afghanistan.

教育活動

At TMGH, I teach master students about essential skills and tropical medicine (clinical bacteriology and molecular diagnostic technique), and organize and facilitate clinical case discussion between the students and doctors in San Lazaro Hospital (Philippians), Bach Mai Hospital (Vietnam) and National Center for Global Health and Medicine (Japan).

Previously I taught advanced paediatric life support (APLS) course to junior medical doctors in Siddhartha Children and Women Hospital, Nepal and child health and management of malnutrition to medical and nursing staffs in Djibouti.

研究活動

I have studied the distribution of pneumococcal serotypes in hospital admitted children and adults in Japan, Vietnam and Afghanistan with a particular focus on the estimation of pneumococcal vaccine coverage.

After I participated in relief efforts following the earthquake in 2015 in Nepal, we are developing a research collaboration with Siddhi Memorial Hospital, Bhaktapur (http://smf.org.np). The focus is on childhood infectious diseases and malnutrition. We are supporting hospital disease surveillance and have conducted nutritional assessments of children who were displaced by the earthquake and living under temporary shelters.

At TMGH, we are establishing new diagnostic assays for typhoid fever based on real-time PCR and loop-mediated isothermal amplification (LAMP). We plan to evaluate these assays in Nepal and other field sites.

bhim_1
Picture1:Disease surveillance in Siddhi Memorial Hospital, Bhaktapur, Nepal.

 

bhim_2
Picture 2: Nutritional assessment of children in temporary shelters in Bhaktapur after 2015 earthquake in Nepal.

 

現在の主な研究活動地域

  • Japan
  • Nepal
  • Afghanistan

最近の5つの出版物

  1. Kakiuchi S, Suzuki M, Dhoubhadel BG, Furumoto A, Ito H, Kei Matsuki, Tsuchihashi Y, Asoh N, Yasunami M, Ariyoshi K, Morimoto K, Adult Pneumonia Study Group-Japan (2018). Accuracy of high-throughput nanofluidic PCR-based pneumococcal serotyping and quantification assays using sputum samples for diagnosing vaccine serotype pneumococcal pneumonia: analyses by composite diagnostic standards and Bayesian latent class models, J Clin Microbiol.
  2. Shrestha D, Dhoubhadel BG, Parry CM, Prajapati B, Ariyoshi K, Mahaseth C (2017). Predicting deaths in a resource-limited neonatal intensive care unit in Nepal, Trans R Soc Trop Med Hyg.
  3. Zabihullah R, Dhoubhadel BG, Rauf RA, Shafiq SA, Suzuki M, Watanabe K, Yoshida LM, Yasunami M, Zabihullah S, Parry CM, Mirwais R, Ariyoshi K (2017). Risk for death among children with pneumonia, Afghanistan, Emerg Infect Dis.
  4. Suzuki M, Dhoubhadel BG, Ishifuji T, Yasunami M, Yaegashi M, Asoh N, Ishida M, Hamaguchi S, Aoshima M, Ariyoshi K, Morimoto K; Adult Pneumonia Study Group-Japan (APSG-J) (2016). Serotype-specific effectiveness of the 23-valent pneumococcal polysaccharide vaccine against pneumococcal pneumonia among adults aged ≥65 years: a multicenter prospective test-negative design study, Lancet Infect Dis.
  5. Dhoubhadel BG, Yasunami M, Nguyen HA, Suzuki M, Vu TH, Thi Thuy Nguyen A, Dang DA, Yoshida LM, Ariyoshi K (2014) Bacterial Load of Pneumococcal Serotypes Correlates with Their Prevalence and Multiple Serotypes is Associated with Acute Respiratory Infections, PLoS One.

すべての出版物へのリンク

http://www.ncbi.nlm.nih.gov/sites/myncbi/1pMFjL8tdMn55/bibliography/40287257/public/?sort=date&direction=ascending

メッセージ

Clinical infectious diseases, child health and vaccination are some of the inter-related exciting fields of global health.
We have been working in these areas and found that there are lots to discover, learn and contribute on these topics globally.
We hope you will find them interesting and contribute while you study here at TMGH. Welcome!

増田 研 准教授

    修了課程: 修了年度:

取得学位・資格

PhD in Social Anthropology

ResearchGate/LinkedInアカウント

https://www.linkedin.com/pub/ken-masuda/27/763/a83

他所属

School of Global Humanities and Social Sciences, Nagasaki University

経歴

Socio-anthropological study on history, socio-cultural dynamics, inter-ethnic conflict, modernization and development among the Banna in southern Ethiopia since 1993. Study on medical anthropology and medical pluralism since 2008. Study on population aging and elderly care since 2012.

教育活動

  • Teaching medical anthropology at TMGH and supervising master thesis at the International Health Development program. My students have carried out researches in Ethiopia, Kenya, Burkina Faso, Bangladesh, the Philippines, and Cambodia.
  • Teaching Environmental anthropology at the Faculty of Environmental Studies and African Study at the School of Global Humanities and Social Sciences.

研究活動

I am currently involved in research teams on global aging, especially focusing on future aging and social welfare in Africa. Both qualitative and quantitative research on elderly life, health, care and social protection will be carried out in East Africa; Ethiopia, Kenya, Uganda, and Zambia.

現在の主な研究活動地域

  • Ethiopia (1993-Now)
  • Kenya (2012-Now)
  • Tanzania (2015-Now)
  • Nagasaki (2004- Now)

メッセージ

1993年から北東アフリカのエチオピアに渡り,南部の少数民族バンナで,まさに現在進行中の近代化プロセスを研究してきました。辺境の小規模社会がグローバルなシステムに接続し,呑み込まれていく様子を見ていると,開発の良い面も悪い面も見えてきます。このコースでは伝統文化と社会のあり方,近代化と開発,そして「医学的でないやり方」について考えながら,人類学的な国際保健へのアプローチを教えています。

松井 三明 准教授

    修了課程: 修了年度:

取得学位・資格

MD, MSc, PhD

ResearchGate/LinkedInアカウント

mmatsui@nagasaki-u.ac.jp

経歴

I have been working in the field of maternal health. Pregnancy and childbirth are mostly physiological processes. In some cases, however, there are pathological aspects as well. Both physiology and pathology must be taken into account when considering maternal health. Unfortunately, only pathological phenomenon is focused on, as exemplified in the saying that “Every pregnancy is a risk”. Therefore, there is a huge misuse of medical interventions observed, both in developing and industrialized countries. We should strive to find an optimal point in between the two, keeping in mind that that point is variable. There is no “magic bullet” in the field of public health. We must think together how we can change this world.

教育活動

I am in charge of the two following modules

  • “Reproductive Health and Gender”Objective: to obtain necessary knowledge in order to control maternal morbidity and mortality and gender issues in developing countries.
  • “Program and Project Management”Objective: to obtain necessary knowledge and skill to manage public health program/projects in developing countries.

研究活動

  • “The impact of the improvement of the quality of care in maternity on maternal and neonatal health in health centers in Cambodia.”Outline – Evidence-based maternity and neonatal care is not well provided at health facilities in many developing countries, therefore the quality of care is substandard. However, international societies put immense pressure on the promotion of facility-based delivery regardless of the quality of care. We carry out an evaluation of maternal and neonatal conditions during labor and the postpartum period and observe the changes after an intervention, which aims to improve the quality of care during maternity.
  • “Factors of chronic malnutrition among children under 2 years old in rural Cambodia.”Outline – Approximately one out of four children aged 24 months demonstrated being “underweight” (weight for age < -2 s.d.) in rural Cambodia. This rate progressively increased with the age of the children. This study employs a prospective design to observe the changes of weight related to age and its associated factors in rural Cambodia.

現在の主な研究活動地域

Cambodia (capital – Phnom Penh, rural – Prey Veng province)

最近の5つの出版物

  1. Suto M, Takehara K, Misago C, Matsui M. Prevalence of perineal lacerations in women giving birth at midwife-led birth centers in Japan: A retrospective descriptive study. J midwife women health. in press(2015)
  2. Noguchi M, Matsui M, Osanai Y, Horikoshi Y, Takehara K, Misago C. Women-friendly childbirth experience Cambodia. J Int Health 29(4): 81.(2014)
  3. Matsui M, Sokhan U, Keth LS, Tung R.Equity gap in utilisation of emergency obstetric care service in Cambodia, from 2007 to 2009. Trop Med Int Health. 18(suppl 1): 187.(2013)
  4. Iwamoto A, Matsui M, Okabayashi H. Review of maternal, neonatal and child health integrated services in the southern four provinces in Lao PDR. Trop Med Int Health. 18(suppl 1): 186.(2013)
  5. Honda A, Randaoharison PG, Matsui M. Affordability of emergency obstetric and neonatal care at public hospitals in Madagascar. Reprod Health Matters. 19: 10-20.(2011)

メッセージ

開発途上国での妊娠,出産を安全にすること,また産む女性,生まれてくる子ども,そして家族にとってより良いものにしていくことを研究課題としています。
妊娠と出産は生理学的な事象ですが,時に合併症を伴います。よって正常から異常までの広い範囲に対応することが必要です。これらの対応とは,単に医学的なものだけではなく,次世代へ生をつなげようとする人々への、さらには社会に対しての関わりであり,そこに携わるひとりひとりの姿勢,ありようが問われるものです。
公衆衛生に関わるということは,すなわちクリアカットには割り切れない「社会的存在」としての人間の課題に取り組むことであり,この点に学問のおもしろさがあるのです。

水上 修作 准教授

    修了課程: 修了年度:

取得学位・資格

博士(医学)長崎大学、医師

個人/所属ウェブページ

http://www.tm.nagasaki-u.ac.jp/nekken/departments/shionogi-immuneregu.html

ResearchGate/LinkedInアカウント

https://researchmap.jp/ShusakuMizukami
https://www.linkedin.com/in/shusaku-mizukami-772623166/

他所属

長崎大学熱帯医学研究所 シオノギグローバル感染症連携部門 免疫病態制御学分野

経歴

平成14年長崎大学医学部卒業後、同医歯薬学総合研究科博士課程を修了。平成20年より理化学研究所免疫・アレルギー科学総合研究センター特別研究員。平成23年より岡山大学大学院医歯薬学総合研究科助教。平成26年より長崎大学熱帯医学研究所助教。平成31年より同准教授(免疫病態制御学分野主任研究者)。

教育活動

長崎大学にて感染免疫学、ワクチン学、遺伝子工学を講義

研究活動

熱帯病を対象とした免疫学的解析、ワクチン開発・創薬研究

現在の主な研究活動地域

日本、東南アジア、アフリカ

最近の5つの出版物

  1. Kinetics of CD4+ T Helper and CD8+ Effector T Cell Responses in Acute Dengue Patients. Manh DH, Weiss LN, Thuong NV, Mizukami S, Dumre SP, Quang LC, Thanh LC, Thang CM, Huu PT, Phuc LH, Nhung CTH, Mai NT, Truong NQ, Ngu VTT, Quoc DK, Ha TTN, Ton T, An TV, Halhouli O, Quynh LN, Gomaa KM, Karbwang J, Huong VYQ, Huy NT and Hirayama K. Front Immunol. 2020 Sep 24. https://doi.org/10.3389/fimmu.2020.01980.
  2. Impact of political conflict on tuberculosis notifications in North-east Nigeria, Adamawa State: a 7-year retrospective analysis. Pembi E, John S, Dumre SP, Ahmadu BU, Vuong NL, Ebied A, Mizukami S, Huy NT, Cuevas LE, Hirayama K. BMJ Open. 2020 Sep 16;10(9):e035263. doi: 10.1136/bmjopen-2019-035263.
  3. Knowledge, behaviour and attitudes towards Chagas disease among the Bolivian migrant population living in Japan: a cross-sectional study. Iglesias Rodríguez IM, Mizukami S, Manh DH, Thuan TM, Justiniano HA, Miura S, Ito G, Huy NT, Smith C, Hirayama K. BMJ Open. 2020 Sep 14;10(9):e032546. doi: 10.1136/bmjopen-2019-032546.
  4. Anti-malarial activity of traditional Kampo medicine Coptis rhizome extract and its major active compounds. Teklemichael AA, Mizukami S, Toume K, Mosaddeque F, Kamel MG, Kaneko O, Komatsu K, Karbwang J, Huy NT, Hirayama K. Malar J. 2020 Jun 8;19(1):204. doi: 10.1186/s12936-020-03273-x.
  5. IL-17A, a possible biomarker for the evaluation of treatment response in Trypanosoma cruzi infected children: A 12-months follow-up study in Bolivia. Vásquez Velásquez C, Russomando G, Espínola EE, Sanchez Z, Mochizuki K, Roca Y, Revollo J, Guzman A, Quiroga B, Rios Morgan S, Vargas Ortiz R, Zambrana Ortega A, Espinoza E, Nishizawa JE, Kamel MG, Kikuchi M, Mizukami S, Na-Bangchang K, Tien Huy N, Hirayama K. PLoS Negl Trop Dis. 2019 Sep 25;13(9):e0007715. doi: 10.1371/journal.pntd.0007715. eCollection 2019 Sep.

メッセージ

社会に還元できる基礎研究を進めていきたいと思います。

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