Associate Professor Yuki Takamatsu

Speciality / Research theme / Keywords

Virology, Highly pathogenic viruses, Live cell imaging

Supervision

Masters Programme

Qualifications

Doctor of Medical Science, Medical Doctor license

Personal/work Web page addresses

Currently updating (to be open by the end of April/May 2022)

Background

B.A. (Medicine), Yamaguchi University
D., Nagasaki University, Graduate School of Biomedical Sciences (Virology, Institute of Tropical Medicine)
Postdoctoral researcher at the Institute of Virology, Philipp Universität Marburg (JSPS Postdoctoral Fellow), Institute for Frontier Life and Medical Sciences, Kyoto University (JSPS SPD), and Senior Researcher, Department of Virology I, National Institute of Infectious Diseases (NIID), Nagasaki University. Current position from November 2021.

Teaching

Has supervised students (partially) at Philipp Universität Marburg, Nagasaki University Institute of Tropical Medicine, Institute for Virus and Regenerative Medicine, Kyoto University, and National Institute of Infectious Diseases. From 2022, lectures on general and specific virology at the Master of Tropical Medicine and TMGH From 2022, supervises master and doctoral students in Nekken-Virology.

Research

BSL-4 research, highly pathogenic virus research, viral replication mechanisms, viral pathogenicity mechanisms.

The country/countries where you work currently

Highly pathogenic viruses, intracellular dynamics analysis, replication mechanism analysis, molecular mechanism analysis, various microscopy analyses.

Five MOST IMPORTANT/INTERESTING recent publications

1. Nabeshima T, Ngwe Tun MM, Thuy NTT, Hang NLK, Mai LTQ, Hasebe F, Takamatsu Y. Nagasaki University Vietnam Research Group. An outbreak of a novel lineage of dengue virus 2 in Vietnam in 2022. Journal of Medical Virology. 2023; 95(11): e29255.
2. Hu S, Fujita-Fujiharu Y, Sugita Y, Wendt L, Muramoto Y, Nakano M, Hoenen T, Noda T. Cryoelectron microscopic structure of the nucleoprotein-RNA complex of the European filovirus, Lloviu virus. PNAS Nexus. 2023; 2(4): pgad120.
3. Takamatsu Y, Yoshikawa T, Kurosu T, Fukushi S, Nagata N, Shimojima M, Ebihara H, Saijo M, Noda T. Role of VP30 Phosphorylation in Ebola Virus Nucleocapsid Assembly and Transport. Journal of Virology. 2022; 96(17): e0108322.
4. Fujita-Fujiharu Y, Sugita Y, Takamatsu Y, Houri K, Igarashi M, Muramoto Y, Nakano M, Tsunoda Y, Taniguchi I, Becker S, Noda T. Structural insight into Marburg virus nucleoprotein-RNA complex formation. Nature Communications. 2022; 13(1):1191.
5. Takamatsu Y, Krähling V, Kolesnikova L, Halwe S, Lier C, Baumeister S, Noda T, Biedenkopf N, Becker S. Serine-Arginine Protein Kinase 1 Regulates Ebola Virus Transcription. mBio. 2020; 11(1): e02565-19.

Message

This year, we have renewed both our Lab and our research activities. In addition to conventional virus research methods (basic research on epidemiology, diagnosis and treatment), we focus on visualization of highly pathogenic viruses using high-resolution microscopy (e.g. live cell imaging). To observe the lifestyles of small viruses, which are normally impossible to see through, using advanced microscopy techniques. If you are interested in our research, such as “want to see viruses”, “am interested in their movements” or “kind of interest in a microscope”, we would like to hear from you. If you are interested in our research, please come and visit us.