Associate Professor Shusaku Mizukami

Speciality / Research theme / Keywords
Immunology, Vaccine development., Cellular immunity
Masters Programme


M.D., Ph.D.

Personal/Work Web page addresses


Research gate or Linked-in account links



Associate professor (Principal investigator), Department of Immune Regulation, Shionogi Global Infectious Diseases Division (SHINE), Institute of Tropical Medicine (NEKKEN), Nagasaki University


Postdoctoral Researcher, Research institute for Allergy and Immunology (RCAI), RIKEN, 2008-2011. Assistant professor, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2011-2014. Assistant professor, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 2014-2019. Associate professor (Principal investigator of Department of Immune Regulation), NEKKEN, Nagasaki University.


Immunology, Biotechnology (Nagasaki University)


Immunological analysis and vaccine/drug development on tropical medicine are my research field. Especially, my current top priority is malaria vaccine development.

The country/countries where you work currently

Japan, Vietnam, Philippines, DRC

Five MOST IMPORTANT/INTERESTING recent publications

  1. Anti-Trypanosoma cruzi activity of Coptis rhizome extract and its constituents. Tayama Y, Mizukami S, Toume K, Komatsu K, Yanagi T, Nara T, Tieu P, Huy NT, Hamano S, Hirayama K. Trop Med Health;51(1):12,2023.
  2. Focused ultrasound/microbubbles-assisted BBB opening enhances LNP-mediated mRNA delivery to brain. Ogawa K, Kato N, Yoshida M, Hiu T, Matsuo T, Mizukami S, Omata D, Suzuki R, Maruyama K, Mukai H, Kawakami S. J Control Release;348:34-41,2022.
  3. Phenylpropanoid-conjugated iridoid glucosides from leaves of Morinda morindoides. Hashim Y, Toume K, Mizukami S, Kitami T, Taniguchi M, Teklemichael AA, Tayama Y, Huy NT, Lami JN, Bodi JM, Hirayama K, Komatsu K. J Nat Med;76(1):281-290,2022.
  4. 2D-quantitative structure-activity relationships model using PLS method for anti-malarial activities of anti-haemozoin compounds. Nguyen PTV, Van Dat T, Mizukami S, Nguyen DLH, Mosaddeque F, Kim SN, Nguyen DHB, Đinh OT, Vo TL, Nguyen GLT, Quoc Duong C, Mizuta S, Tam DNH, Truong MP, Huy NT, Hirayama K.Malar J;20(1):264,2021.
  5. Kinetics of CD4+ T Helper and CD8+ Effector T Cell Responses in Acute Dengue Patients. Manh DH, Weiss LN, Thuong NV, Mizukami S, Dumre SP, Luong QC, Thanh LC, Thang CM, Huu PT, Phuc LH, Nhung CTH, Mai NT, Truong NQ, Ngu VTT, Quoc DK, Ha TTN, Ton T, An TV, Halhouli O, Quynh LN, Kamel MG, Karbwang J, Huong VTQ, Huy NT, Hirayama K. Front Immunol;11:1980,2020.


Basic research makes people happy!