Professor Hiroki Ozawa

Speciality / Research theme / Keywords
Masters Programme


M.D., Ph.D.

Personal/work Web page addresses



  • Division of Neuropsychiatry
  • Unit of Translational Medicine
  • Graduate School of Biomedical Sciences



  • 1985/03 School of Medicine, Sapporo Medical University
  • 1990/03 Ph.D. Graduate School of Medicine, Sapporo Medical University


  • 1993/04-1999/12  Lecturer , Dept. Neuropsychiatry, Sapporo Medical University
  • 2000/01-2001/11 Assistant Professor, Dept. Neuropsychiatry, Sapporo Medical University
  • 2001/12-2004/09 Associate Professor, Dept. Neuropsychiatry, Sapporo Medical University
  • 2003/10 – pres.  Professor, Division of Neuropsychiatry, Unit of Translational Medicine, Graduate School of Biomedical Sciences, Nagasaki University


  • Psychiatry, Global mental health
  • mhGAP Intervention Guide for mental, neurological and substance use disorders in non-specialized health settings


  • Our department executes a long-term investigation of epidemiology such as the prognosis of patients who suffer from schizophrenia, their mental and physical health conditions, which are caused by Atomic bomb or the eruption of Unzen Fugendake.
  • The molecule, inherited historical research and investigation on schizophrenia, and the cause of a causal mental disease such as Bi-polarity depression are the main streams of research in our department now.
  • In the latter researches we investigate the correlation of structural abnormality and the psychological illness of the brain, and examine how the mental disease medicine affects the neural stem cells. We try to connect the three of them.
  • For instance, about 10 percent of the victims from the disaster of the Fugendake eruption are still suffering from mental symptoms, on the other hand many of them have recovered from the disaster. In addition, the more that the treatment period is prolonged, the worse the prognosis of schizophrenia, therefore it is important that diagnosis and treatment are conducted as early as possible.
  • Using genetics and biological research, I would like to verify the factors in this epidemiologic study.

The country/countries where you work currently

  • China
  • Indonesia
  • Thai
  • Singapore
  • Myanmar

Five MOST IMPORTANT/INTERESTING recent publications

See researchmap


In this laboratory, we are conducting researches on long-term outcomes for schizophrenic patients and the mental/physical health of victims of the atomic bombs and the disaster on Mt. Fugen.

Current main themes are the molecular/genetic study of schizophrenia and pathobiologic study to discover the causes of endogenous mental disorders including bipolar disorder.

In recent studies, I have been examining the effects of antipsychotic drugs on neural stem cells, studying the correlation between mental disorder and structural abnormality in the brain. In the future, I plan to establish a more academic research system by integrating these three studies.

For example, approx. 10% of the victims of the Mt. Fugen disaster still suffer from psychoneurosis, even though most of them have already recovered. Additionally, the prognosis of schizophrenia worsens as the treatment period lengthens, demonstrating the importance of early diagnosis and early treatment.

I intend to discover these factors in epidemiologic study through genetic and biological studies.