Associate Professor Hirotomo Yamanashi

Speciality / Research theme / Keywords

General Medicine, Clinical Infectious Disease
Frailty, Sarcopenia, Multimorbidity and chronic infectious diseases

Supervision

Masters ProgrammeDoctoral Programme

Qualifications

MD, PhD

Personal/work Web page addresses

http://www.mh.nagasaki-u.ac.jp/soshin/
http://www.tm.nagasaki-u.ac.jp/internal/

Affiliation(s)

Department of General Medicine, Nagasaki University Graduate School of Biomedical Sciences
Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University
Department of General Medicine/ Infectious Diseases, Nagasaki University Hospital

Background

• 2021-Present
  Associate Professor of Department of General Medicine
• 2018-2021
  Senior lecturer of Department of General Medicine
  (Japan Disaster Relief Infectious Diseases Response Team in 2019)
• 2013-2018
  Assistant professor of Department of Island and Community Medicine
  (Médecins Sans Frontières in 2016, 2017)
• 2012-2013
  Staff doctor of Department of Infectious Diseases, Nagasaki University Hospital
• 2011-2012
  Director of Ohi Kyodo Clinic
• 2008-2011
  Senior Resident of Centre for Family Medicine Development Tokyo
• 2006-2008
  Junior Doctor of Yokosuka Uwamachi General Hospital

Teaching

Giving lectures (General Medicine, Infectious diseases, and Community Health) in TMGH, Nagasaki University Graduate School of Biomedical Sciences and Nagasaki University Hospital.
Supervisor of Joint Nagasaki-LSHTM PhD Programme.

Research

I have been studying epidemiological studies in Vietnam, India, and Japan, particularly on primary care, geriatric medicine, clinical infectious diseases. I have participated in Nagasaki Islands Study since 2014, which is a prospective cohort study aiming to investigate genetic susceptibility to atherosclerosis, cardiovascular diseases, rheumatoid arthritis, and frail & sarcopenia. I am also engaged in international study collaborating with the Andhra Pradesh Children and Parents Study (PI: Professor Sanjay Kinra, LSHTM).

The country/countries where you work currently

Goto City, Nagasaki, Japan/ Hyderabad, India

Five MOST IMPORTANT/INTERESTING recent publications

1. Yamanashi H, Akabame S, Miyata J, Honda Y, Nonaka F, Shimizu Y, Nakamichi S, Kawashiri SY, Tamai M, Arima K, Kawakami A, Aoyagi K, Maeda T. Association between Epstein-Barr virus serological reactivation and psychological distress: a cross-sectional study of Japanese community-dwelling older adults. Aging (Albany NY). 2022 Oct 21;14(20):8258-8269. doi: 10.18632/aging.204345. Epub 2022 Oct 21. PMID: 36279393; PMCID: PMC9648801.
2.  Shimizu Y, Yamanashi H, Miyata J, Takada M, Noguchi Y, Honda Y, Nonaka F, Nakamichi S, Nagata Y, Maeda T. VEGF Polymorphism rs3025039 and Human T-Cell Leukemia Virus 1 (HTLV-1) Infection among Older Japanese Individuals: A Cross-Sectional Study. Bioengineering (Basel). 2022 Oct 6;9(10):527. doi: 10.3390/bioengineering9100527. PMID: 36290496; PMCID: PMC9598135.
3. Yamanashi H, Nobusue K, Nonaka F, Honda Y, Shimizu Y, Kawashiri SY, Izumida M, Kubo Y, Tamai M, Nagata Y, Yanagihara K, Kulkarni B, Kinra S, Kawakami A, Maeda T. Human T-cell lymphotropic virus type-1 infection associated with sarcopenia: community-based cross-sectional study in Goto, Japan. Aging (Albany NY). 2020 Jul 24;12(15):15504-15513. doi: 10.18632/aging.103736. Epub 2020 Jul 24. PMID: 32706758; PMCID: PMC7467371.
4. Yamanashi H, Nobusue K, Nonaka F, Honda Y, Shimizu Y, Kawashiri SY, Izumida M, Kubo Y, Tamai M, Nagata Y, Yanagihara K, Kulkarni B, Kinra S, Kawakami A, Maeda T. Human T-cell lymphotropic virus type-1 infection associated with sarcopenia: community-based cross-sectional study in Goto, Japan. Aging (Albany NY). 2020 Jul 24;12(15):15504-15513. doi: 10.18632/aging.103736. Epub 2020 Jul 24. PMID: 32706758; PMCID: PMC7467371.
5.  Yamanashi H, Koyamatsu J, Nagayoshi M, Shimizu Y, Kawashiri SY, Kondo H, Fukui S, Tamai M, Sato S, Yanagihara K, Kawakami A, Maeda T. Human T-Cell Leukemia Virus-1 Infection Is Associated With Atherosclerosis as Measured by Carotid Intima-Media Thickness in Japanese Community-Dwelling Older People. Clin Infect Dis. 2018 Jul 2;67(2):291-294. doi: 10.1093/cid/ciy168. PMID: 29529133.

Message

Emerging problems in the super-aged society is age-related functional decline, such as frailty, sarcopenia, and multimorbidity. I am keen to know how we can describe age-related functional decline in each community, and how we can respond to these issues globally in aspects of both clinical medicine and public health.