HOMEProfessor Fuyuki Tokumasu

Faculty

Professor Fuyuki Tokumasu

Speciality / Research theme / Keywords
Lipid metabolism in malaria parasites, Lipid membrane biophysics, High-resolution bioimaging
Supervision
Masters ProgrammeDoctoral Programme

Qualifications

Ph.D. (Human and Environmental Studies)

Personal/work Web page addresses

http://www.tm.nagasaki-u.ac.jp/nekken/departments/shionogi-cellulararchi.html

Research gate or Linked-in account links

https://www.researchgate.net/profile/Fuyuki_Tokumasu
https://www.linkedin.com/in/fuyuki-tokumasu-35a1972b/

Affiliation(s)

Guest Researcher at Department of Lipidomics, University of Tokyo
Visiting Fellow at Lipid Signaling Project, National Center of Global Health and Medicine

Background

  • 1990.8～1994.5 Birmingham-Southern College (U.S.A.）B.S., Major: Physics, Minor: Mathematics
  • 1994.9～1996.3 The Ohio State University(U.S.A.）M.S., Biophysics Program
  • 1996.4～2000.1 Graduate School of Human and Environmental Studies, Kyoto University. Ph.D.
  • 2000.2～2001.1 National Institutes of Health (NIH), Visiting Fellow
  • 2001.2～2003.1 JSPS Research Fellow (NIH)
  • 2003.2～2006.1 National Institutes of Health (NIH), Research Fellow
  • 2006.4～2013.2 National Institute of Standards and Technology, Guest Researcher
  • 2006.1～2014.3 National Institutes of Health (NIH), Staff Scientist
  • 2007.2～2014.3 National Institutes of Health(NIH), Leading Investigator, Biochemical and Biophysical Parasitology Program
  • 2014.4～2019.3 Associate Professor, Department of Lipidomics, University Tokyo
  • 2014.4～Current Visiting Fellow at Lipid Signaling Project, National Center of Global Health and Medicine
  • 2019.4～Current Guest Researcher at Department of Lipidomics, University of Tokyo
  • 2019.4～Current Professor, Department of Cellular Architecture Studies, Institute of Tropical Medicine, Nagasaki University.  Co-appointed in TMGH

Teaching

Basic Human Biology, Global Health Seminar
Coordinator, Infectious Diseases-Research-in-Progress Seminar (IDRiPS)

Research

Lipid biology in Plasmodium parasites using high-resolution bioimaging, lipidomics analyses by mass spectroscopy, gene manipulation techniques and biophysical analyses for numerical and image data.

The country/countries where you work currently

Japan and USA

Five MOST IMPORTANT/INTERESTING recent publications

(*Corresponding Author, ¶Equal contributed Authors)

  • N. Iso-o*¶, K. Komatsuya¶, F. Tokumasu*¶, N. Isoo, T. Ishigaki, H. Yasui, H. Yotsuyanagi, M. Hara, K. Kita* (2021) Malaria parasites hijack host receptors from exosomes to capture lipoproteins. Cellular and Molecular Basis in Parasitic Diseases Control: Research Trends in Front. Cell Dev. Biol. 9: 749153
  • F. Tokumasu*, E.H. Hayakawa, J. Fukumoto, S.M. Tokuoka, S. Miyazaki* (2021) Creative interior design by Plasmodium falciparum: Lipid metabolism and the parasite’s secret chamber. Parasitol. Int. 83: 102369
  • E.D. Hartuti, T. Sakura, M.S.O. Tagod, E. Yoshida, X. Wang, K. Mochizuki, R. Acharjee, Y. Matsuo, F. Tokumasu, M. Mori, D. Waluyo, K. Shiomi, T. Nozaki, S. Hamano, T. Shiba, K. Kita and D.K. Inaoka (2021) Identification of 3,4-dihydro-2H,6H-pyrimido[1,2-c][1, 3]benzothiazin-6-imine derivatives as novel selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. Int. J. Mol. Sci. 22: 7236
  • T.Q Tanaka¶, S.M. Tokuoka, D. Nakatani, F. Hamano, S. Kawazu, T.E. Wellems, K. Kita, T. Shimizu, F. Tokumasu*,¶, (2019) Polyunsaturated fatty acids promote Plasmodium falciparum gametocytogenesis Biology Open, 8: bio042259 (Early Electronic Version, Jun. 20, 2019)
  • H. Shindou, H. Koso, J. Sasaki, H. Nakanishi, H. Sagara, K. M. Nakagawa, Y. Takahashi, D. Hishikawa, Y. Iizuka-Hishikawa, F. Tokumasu, H. Noguchi, S. Watanabe, T. Sasaki, & T. Shimizu (2017) Docosahexaenoic acid preserves visual function by maintaining correct disc morphology in retinal photoreceptor cells. J. Biol. Chem., 292: 12054-12064.

Message

There are many occasions where basic biological knowledge is critical for diagnosis, drug developments, treatment policy, and understandings of biology in organisms that spread diseases. I would like everybody who studies global health becomes very familiar with basic biology of pathogens for expanding your future carrier paths and flexibility.

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